Biophysical and structural characterization of the impacts of MET phosphorylation on tepotinib binding

Publication date: Available online 6 October 2023

Source: Journal of Biological Chemistry

Author(s): Ulrich Grädler, Daniel Schwarz, Ansgar Wegener, Thomas Eichhorn, Tiago M. Bandeiras, Micael C. Freitas, Alfred Lammens, Oleg Ganichkin, Martin Augustin, Stefano Minguzzi, Frank Becker, Jörg Bomke

‘Affimer’ synthetic protein scaffolds block oxidized LDL binding to the LOX-1 scavenger receptor and inhibit ERK1/2 activation

Publication date: Available online 5 October 2023

Source: Journal of Biological Chemistry

Author(s): Barnaby W.R. Roper, Christian Tiede, Izma Abdul-Zani, Gary A. Cuthbert, Dhananjay Jade, Ahmed Al-Aufi, William R. Critchley, Queen Saikia, Shervanthi Homer-Vanniasinkam, Tatsuya Sawamura, Michael J. McPherson, Michael A. Harrison, Darren C. Tomlinson, Sreenivasan Ponnambalam

Mycobacterial RNase E cleaves with a distinct sequence preference and controls the degradation rates of most <em>Mycolicibacterium smegmatis</em> mRNAs

Publication date: Available online 5 October 2023

Source: Journal of Biological Chemistry

Author(s): Ying Zhou, Huaming Sun, Abigail R. Rapiejko, Diego A. Vargas-Blanco, Maria Carla Martini, Michael R. Chase, Samantha R. Joubran, Alexa B. Davis, Joseph P. Dainis, Jessica M. Kelly, Thomas R. Ioerger, Louis A. Roberts, Sarah M. Fortune, Scarlet S. Shell

Bacterial RNA-free RNase P: structural and functional characterization of multiple oligomeric forms of a minimal protein-only ribonuclease P

Publication date: Available online 6 October 2023

Source: Journal of Biological Chemistry

Author(s): Catherine A. Wilhelm, Leena Mallik, Abigail L. Kelly, Shayna Brotzman, Johnny Mendoza, Anna G. Anders, Suada Leskaj, Carmen Castillo, Brandon T. Ruotolo, Michael A. Cianfrocco, Markos Koutmos