Ubiquitin specific protease 11 structure in complex with an engineered substrate mimetic reveals a molecular feature for deubiquitination selectivity

Publication date: Available online 28 September 2023

Source: Journal of Biological Chemistry

Author(s): Sigrun K. Maurer, Matthias P. Mayer, Stephanie J. Ward, Sana Boudjema, Mohamed Halawa, Jiatong Zhang, Simon G. Caulton, Jonas Emsley, Ingrid Dreveny

Competition for cysteine acylation by C16:0 and C18:0 derived lipids is a global phenomenon in the proteome

Publication date: September 2023

Source: Journal of Biological Chemistry, Volume 299, Issue 9

Author(s): Hana Nůsková, Fabiola Garcia Cortizo, Lena Sophie Schwenker, Timo Sachsenheimer, Egor E. Diakonov, Marcel Tiebe, Martin Schneider, Jasmin Lohbeck, Carissa Reid, Annette Kopp-Schneider, Dominic Helm, Britta Brügger, Aubry K. Miller, Aurelio A. Teleman

Withdrawal: Hypoxia-inducible factor 1 (HIF-1) promotes extracellular matrix remodeling under hypoxic conditions by inducing <em>P4HA1</em>, <em>P4HA2</em>, and <em>PLOD2</em> expression in fibroblasts

Publication date: September 2023

Source: Journal of Biological Chemistry, Volume 299, Issue 9

Author(s): Daniele M. Gilkes, Saumendra Bajpai, Pallavi Chaturvedi, Denis Wirtz, Gregg L. Semenza