Monthly Archives: October 2023

Flexibility in the bridge of chalcone derivatives is important for the inhibition of cellular growth

Posted on by

Publication date: 15 October 2023

Source: Bioorganic & Medicinal Chemistry Letters, Volume 95

Author(s): Trevor M. Stantliff, Amber Hill, Mary Elaine Kuo, Hadley E. Neal, Tighe C. Harrod, Katy Goens, Mark Mashuta, Anna M. Christianson, Amanda J. Krzysiak

Discovery of marine phidianidine-based Nrf2 activators and their potential against oxLDL- and HG-induced injury in HUVECs

Posted on by

Publication date: 15 October 2023

Source: Bioorganic & Medicinal Chemistry Letters, Volume 95

Author(s): Juan Zhang, Yong-Si Cai, Hua-Long Ji, Mengqi Ma, Jin-He Zhang, Zhi-Qiang Cheng, Kai-Ming Wang, Cheng-Shi Jiang, Chunlin Zhuang, Yang Hu, Ning Meng

Design, synthesis and biological evaluation of chalcone derivatives as potent and orally active hCYP3A4 inhibitors

Posted on by

Publication date: 15 October 2023

Source: Bioorganic & Medicinal Chemistry Letters, Volume 95

Author(s): Shiwei Lu, Feng Zhang, Jiahao Gong, Jian Huang, Guanghao Zhu, Yitian Zhao, Qi Jia, Yiming Li, Bo Li, Kaixian Chen, Weiliang Zhu, Guangbo Ge

Synthesis and anti-tumor activities in human leukemia-derived cells of polyenylpyrroles with a methyl group at the conjugated polyene terminus

Posted on by

Publication date: 15 October 2023

Source: Bioorganic & Medicinal Chemistry Letters, Volume 95

Author(s): Tomoya Higashi, Chihiro Yoshida, Yoshifumi Hachiro, Chihiro Nakata, Azusa Takechi, Takuya Yagi, Kazuya Miyashita, Nobuo Kitada, Rika Obata, Takashi Hirano, Takahiko Hara, Shojiro A. Maki