Publication date: 15 November 2023
Source: Bioorganic & Medicinal Chemistry Letters, Volume 96
Author(s): Gyeong Han Jeong, Hanui Lee, Hong-Ki Lee, Hyo Jin Choi, Byung Yeoup Chung, Hyoung-Woo Bai
Monthly Archives: October 2023
Benzimidazole derivatives as tubulin polymerization inhibitors: Design, synthesis and <em>in vitro</em> cytotoxicity studies
Publication date: 15 November 2023
Source: Bioorganic & Medicinal Chemistry Letters, Volume 96
Author(s): Kritika Laxmikeshav, Ziaur Rahman, Ashutosh Mahale, Durgesh Gurukkala Valapil, Pravesh Sharma, Joel George, Regur Phanindranath, Manoj P. Dandekar, Onkar P. Kulkarni, Narayana Nagesh, Nagula Shankaraiah
Total and chemoenzymatic synthesis of the lipodepsipeptide rhizomide A
Publication date: 15 November 2023
Source: Bioorganic & Medicinal Chemistry Letters, Volume 96
Author(s): Corinne A. Lepetit, André R. Paquette, Jordan T. Brazeau-Henrie, Christopher N. Boddy
SAR study of niclosamide derivatives for neuroprotective function in SH-SY5Y neuroblastoma
Publication date: 15 November 2023
Source: Bioorganic & Medicinal Chemistry Letters, Volume 96
Author(s): Shizue Mito, Benxu Cheng, Benjamin A. Garcia, Xin Yee Ooi, Daniela Gonzalez, Tess C. Ruiz, Francisco X. Elisarraras, Andrew Tsin
Discovery of Novel Dual Bruton’s Tyrosine Kinase (BTK) and Janus Kinase 3 (JAK3) Inhibitors as A Promising Strategy for Rheumatoid Arthritis
Publication date: Available online 27 May 2023
Source: Bioorganic & Medicinal Chemistry
Author(s): Tingting Liang, Lifang Cen, Junjie Wang, Ming Cheng, Weibo Guo, Wenjie Wang, Chunqiu Yu, Haifeng Zhang, Yuan Wang, Zhongyan Hao, Jiaming Jin, Yaoyao Wu, Teng Jiang, Qihua Zhu, Yungen Xu
Development of 3-acetylindole Derivatives that Selectively Target BRPF1 as New Inhibitors of Receptor Activator of NF-κB Ligand (RANKL)-Induced Osteoclastogenesis
Publication date: Available online 9 August 2023
Source: Bioorganic & Medicinal Chemistry
Author(s): Wenqiang Zhang, Ruonan Ning, Ting Ran, Qi Peng, Yong Liu, Tao Lu, Yadong Chen, Min Jiang, Yu Jiao
<em>In situ</em> Click Chemistry-based Discovery of 1,2,3-triazole-derived Diarylpyrimidines as Novel HIV-1 NNRTIs by Exploiting the Tolerant Region I in Binding Pocket
Publication date: Available online 23 September 2023
Source: Bioorganic & Medicinal Chemistry
Author(s): Yanying Sun, Da Feng, Zhenzhen Zhou, Tao Zhang, Erik De Clercq, Christophe Pannecouque, Dongwei Kang, Peng Zhan, Xinyong Liu
Target discovery of bioactive natural products with Native-compound-Coupled CNBr-activated Sepharose 4B Beads (NCCB): applications, mechanisms and outlooks
Publication date: Available online 26 September 2023
Source: Bioorganic & Medicinal Chemistry
Author(s): Yueteng Zhang, Junjie Zhang, Menglong Li, Yan Qiao, Wei Wang, Lu Ma, Kangdong Liu
The mechanisms of multidrug resistance of breast cancer and research progress on related reversal agents
Publication date: Available online 30 September 2023
Source: Bioorganic & Medicinal Chemistry
Author(s): Shiwen Yu, Jinling Zheng, Yan Zhang, Dandan Meng, Yujue Wang, Xiaoyu Xu, Na Liang, Shayibai Shabiti, Xu Zhang, Zixi Wang, Zehua Yang, Pengbing Mi, Xing Zheng, Wenjun Li, Hongfei Chen
A novel genetically-encoded bicyclic peptide inhibitor of human urokinase-type plasminogen activator with better cross-reactivity toward the murine orthologue
Publication date: Available online 12 October 2023
Source: Bioorganic & Medicinal Chemistry
Author(s): Ylenia Mazzocato, Stefano Perin, Julia Morales-Sanfrutos, Zhanna Romanyuk, Stefano Pluda, Laura Acquasaliente, Giuseppe Borsato, Vincenzo De Filippis, Alessandro Scarso, Alessandro Angelini