Association between low-sodium salt intervention and long-term blood pressure changes is modified by ENaC genetic variation: A gene-diet interaction analysis in a randomized controlled trial

Food Funct., 2023, Accepted Manuscript
DOI: 10.1039/D3FO02393A, Paper
Hao Sun, Ying Zhou, Shuyi Jiang, Dan Zhao, Huamin Li, Yue Lu, Bing Ma, Bo Zhou
Background: Hypertension is closely associated with excessive sodium intake, and low-sodium salt has been shown to lower blood pressure. However, whether low-sodium salt interacts with genetic variation related to salt...
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Bioavailability and systemic transport of oleanolic acid in humans, formulated as a functional olive oil

Food Funct., 2023, Advance Article
DOI: 10.1039/D3FO02725B, Paper
Open Access Open Access
Aída García-González, Juan Manuel Espinosa-Cabello, Isabel Cerrillo, Emilio Montero-Romero, Juan José Rivas-Melo, Andrea Romero-Báez, María Dolores Jiménez-Andreu, Carmen Amelia Ruíz-Trillo, Ana Rodríguez-Rodríguez, Antonio Jesús Martínez-Ortega, María Del Carmen Roque-Cuellar, Silvia García-Rey, Andrés Jiménez-Sánchez, Miguel Ángel Mangas-Cruz, José Luis Pereira-Cunill, Javier S. Perona, Pedro Pablo García-Luna, José María Castellano
A high bioavailability formulation for oleanolic acid (OA) suggests its potential therapeutic application in humans.
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Association between the dietary inflammatory index and serum perfluoroalkyl and polyfluoroalkyl substance concentrations: evidence from NANHES 2007–2018

Food Funct., 2023, Advance Article
DOI: 10.1039/D3FO01487H, Paper
Ren Zhou, Jiali Peng, Lei Zhang, Yu Sun, Jia Yan, Hong Jiang
This study clarified the association between the three PFASs and DII, highlighting the diverse effects of PFASs on oxidative stress and inflammatory markers across different DII levels.
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Seaweed intake modulates the association between VIPR2 variants and the incidence of metabolic syndrome in middle-aged Koreans

Food Funct., 2023, Advance Article
DOI: 10.1039/D3FO02425C, Paper
Haeun Park, Hyunyu Jeon, Kyung Ju Lee, Choong-Gon Kim, Dayeon Shin
In men with the GG genotype of rs6950857, the highest quintile of seaweed consumption was associated with a decreased incidence of MetS compared with that of the lowest quintile (hazard ratio, 0.78; 95% confidence interval, 0.62–0.98).
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Polyphenols as NLRP3 inflammasome modulators in cardiometabolic diseases: a review of in vivo studies.

Food Funct., 2023, Accepted Manuscript
DOI: 10.1039/D3FO03015F, Review Article
Open Access Open Access
Marisol Villalva, Martínez-García Juan José, Laura Jaime, S. Santoyo, Pablo Pelgrin, Jara Pérez-Jiménez
The nucleotide-binding domain and leucine-rich repeat containing receptors (NLRs) are components of the innate immune system, important to coordinate the inflammatory response. Among them, the NLRP3 could form inflammasomes, a...
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Dietary Lactobacillus rhamnosus GG extracellular vesicles enhance anti-PD-1 immunotherapy efficacy against colorectal cancer

Food Funct., 2023, Accepted Manuscript
DOI: 10.1039/D3FO02018E, Paper
Shun Lu, Jing Xu, Zihao Zhao, Yuheng Guo, Hanwen Zhang, Peter W. Jurutka, Dechun Huang, Chongjiang Cao, Shujie Cheng
There is a need to explore combination therapy to improve the efficacy of immunotherapy for colorectal cancer through food probiotics. In this study, extracellular vesicles (EV) derived from Lactobacillus rhamnosus...
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Effects of maternal high-fat diet on fetal growth, placental nutrient transporters and circular RNA expression profiles

Food Funct., 2023, Advance Article
DOI: 10.1039/D3FO02202A, Paper
Tianle He, Qingyun Chen, Zhidong Yuan, Yulian Yang, Kai Cao, Ju Luo, Guozhong Dong, Xie Peng, Zhenguo Yang
Maternal high-fat diet can affect intrauterine fetal development by regulating body metabolism. Meanwhile, differentially expressed circRNAs in the placenta during a high-fat diet regulate placental nutrient transport and fetal development in multiple ways.
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Effect of red wheat, aleurone, and testa layers on colon cancer biomarkers, nitrosative stress, and gut microbiome composition in rats

Food Funct., 2023, Advance Article
DOI: 10.1039/D3FO03438K, Paper
Chelsey Fiecke, Senay Simsek, Ashok Kumar Sharma, Daniel D. Gallaher
Red wheat, aleurone, and testa reduce aberrant crypt foci and 3-nitrotyrosine and modify gut microbiome composition.
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Casein–phenol interactions occur during digestion and affect bioactive peptide and phenol bioaccessibility

Food Funct., 2023, Advance Article
DOI: 10.1039/D3FO02630B, Paper
Open Access Open Access
Creative Commons Licence  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Aytul Hamzalioglu, Silvia Tagliamonte, Vural Gökmen, Paola Vitaglione
Casein-phenol interaction during digestion provides better bioactive peptide release, antioxidant peptide release and higher bioaccessible total antioxidant activity.
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Simple but novel icariin-loaded pro-glycymicelles as functional food: physicochemical characteristics, in vitro biological activities, and in vivo experimental hyperlipidemic prevention evaluations

Food Funct., 2023, Accepted Manuscript
DOI: 10.1039/D3FO02838K, Paper
Qingchen Cui, Cuicui Wang, Liping Zhou, Yanjun Wei, Zongtao Liu, Xianggen Wu
A novel functional food for hyperlipidemia named icariin (ICA) pro-glycymicelles (ICA-PG) using glycyrrhizin as phytonanomaterials was easily fabricated with great storage, pH, and salt stabilities. ICA-PG can easily dissolve in...
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