2D/2D cobalt vanadate nanoplatelets/S-doped reduced graphene oxide nanosheets composite for the detection of nonsteroidal anti-inflammatory drug: Acetaminophen

Publication date: November 2023

Source: FlatChem, Volume 42

Author(s): Saranvignesh Alagarsamy, Kiruthika Mariappan, Shen-Ming Chen, Rasu Ramachandran, Sandhanasamy Devanesan, Mohamad S. AlSalhi, Prabhakarn Arunachalam, Dhanushkodi Sivaganesh, Jeyaraj Vinoth Kumar, Hsin-Yu Chuang

Exploring positions 6 and 7 of a quinazoline-based scaffold leads to changes in selectivity and potency towards RIPK2/3 kinases

Publication date: 15 November 2023

Source: European Journal of Medicinal Chemistry, Volume 260

Author(s): Mbilo Misehe, Marika Matoušová, Alexandra Dvořáková, Kamil Hercík, Kryštof Škach, Dominika Chalupská, Milan Dejmek, Michal Šála, Miroslav Hájek, Evzen Boura, Helena Mertlíková-Kaiserová, Radim Nencka

Design, synthesis and evaluation of 2-pyrimidinylindole derivatives as anti-obesity agents by regulating lipid metabolism

Publication date: 15 November 2023

Source: European Journal of Medicinal Chemistry, Volume 260

Author(s): Shi-Yao Guo, Li-Yuan Wei, Bing-Bing Song, Yu-Tao Hu, Zhi Jiang, Dan-Dan Zhao, Yao-Hao Xu, Yu-Wei Lin, Shu-Min Xu, Shuo-Bin Chen, Zhi-Shu Huang

Magic shotgun approach to anti-inflammatory pharmacotherapy: Synthesis of novel thienopyrimidine monomers/heterodimer as dual COX-2 and 15-LOX inhibitors endowed with potent antioxidant activity

Publication date: 15 November 2023

Source: European Journal of Medicinal Chemistry, Volume 260

Author(s): Sara Elsayed, Ahmed S. Abdelkhalek, Samar Rezq, Mansour E. Abu Kull, Damian G. Romero, Hend Kothayer