Deuteration of Pd-activated C(sp2)–H bonds in the solid state

Inorg. Chem. Front., 2023, 10,6005-6014
DOI: 10.1039/D3QI00932G, Research Article
Alen Bjelopetrović, Dajana Barišić, Marina Juribašić Kulcsár, Ivan Halasz, Manda Ćurić, Stipe Lukin
A novel approach for deuteration of C–H bonds in a ball mill at ambient temperature using Cys-d4 as D-source is developed. In situ Raman, ex situ spectroscopic and DFT data allowed identification of intermediates and insight into the reaction course.
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