Direct synthesis of phthalimides via palladium-catalysed double carbonylation of o-dihaloarenes with nitroarenes

Chem. Commun., 2023, Advance Article
DOI: 10.1039/D3CC04126C, Communication
Chenwei Liu, Tongshun An, Weiheng Yuan, Huiying Dai, Xiaolan Liang, Zhiping Yin
A novel carbonylation of nitroarenes with o-dihaloarenes was developed to construct various N-substituted phthalimides. Key to the success of this transformation is the use of Mo(CO)6 which serves as both reducing agents and carbonyl sources.
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