Scandium-Catalyzed Chemoselective Carbene Insertion into N−H over S−H: Access to o-Alkylamine-Diaryl Disulfides

Chem. Commun., 2024, Accepted Manuscript
DOI: 10.1039/D4CC00557K, Communication
Haoyang Sun, Junhong Pan, Wenying Zhao, Tong Zhou, Xizhong Song, Jun Lin, Yi Jin
Herein, we report a scandium-catalyzed chemoselective carbene insertion into the N-H bond over S-H bond with disulfide formation. This reaction represents the first example of the synthesis of o-alkylamine-diaryl disulfides...
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