Reductive cross-coupling of N-acyl pyrazole and nitroarene using tetrahydroxydiboron: synthesis of secondary amides

Org. Biomol. Chem., 2023, Advance Article
DOI: 10.1039/D3OB01040F, Paper
Hayeon Moon, Sunwoo Lee
Acyl pyrazoles, in the presence of B2(OH)4, efficiently yield amides when reacted with nitro compounds. The method is versatile, tolerates diverse functional groups, and holds promise for diverse organic molecule synthesis.
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