Trans-Cleavage of CRISPR-Cas12a-Aptamer System for One-Step Antigen Detection

Chem. Commun., 2023, Accepted Manuscript
DOI: 10.1039/D3CC04532C, Communication
Hongxuan Fan, Shihua Luo, Ying Zhu, Jiye Shi, Fangfei Yin, Jiang Li
Rapid detection of prostate-specific antigen (PSA) is pivotal for the early screening of prostate cancer (PCa). Here, we devise a one-step, amplification-free fluorescent detection strategy for PSA, employing the trans-cleavage...
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