Bacterial pseudaminic acid binding to Siglec-10 induces a macrophage interleukin-10 response and suppresses phagocytosis

Chem. Commun., 2024, 60,2930-2933
DOI: 10.1039/D4CC00077C, Communication
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Creative Commons Licence  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
I-Ming Lee, Hsing-Yu Wu, Takashi Angata, Shih-Hsiung Wu
The interaction between pseudaminic acid (Pse) on pathogenic bacteria exopolysaccharide and sialic acid-binding immunoglobulin-type lectin (Siglec)-10 receptor on macrophages induces interleukin 10 (IL-10) release to suppress phagocytosis.
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