A reactive matrix for in situ chemical derivatisation and specific detection of cis-diol compounds by matrix-assisted laser desorption/ionisation mass spectrometry

Analyst, 2023, Advance Article
DOI: 10.1039/D3AN01400B, Paper
Jiajing Chen, Huan Huang, Dan Ouyang, Jiali Lin, Zhuling Chen, Zongwei Cai, Zian Lin
Based on the boronate affinity interaction between boric acid and cis-diols, 6-borono-1-methyl-quinoline-1-ium (BMQI) was designed and used as a reactive matrix for in situ derivatisation and rapid profiling of cis-diol compounds in MALDI-MS.
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