Formation of an instantaneous nick for highly efficient adenylation of oligonucleotides by ligase without subsequent jointing

Chem. Commun., 2024, 60,2942-2945
DOI: 10.1039/D4CC00590B, Communication
Kunling Hu, Wenhua Sun, Hui Chen, Jian Luo, Ziting Song, Ran An, Makoto Komiyama, Xingguo Liang
By forming a nick instantaneously, nucleic acids are efficiently adenylated by T4 DNA ligase without further ligation.
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