Author Archives: Lei Qin

Feasibility of achieving two-electron K–O2 batteries

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Faraday Discuss., 2023, Advance Article
DOI: 10.1039/D3FD00085K, Paper
Lei Qin, Huiling Ao, Yiying Wu
A low-barrier, two-step reaction pathway for peroxide-based K–O chemistry is first realized without any catalysts under the inert argon atmosphere.
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Regulating stereoselectivity of medium-chain dehydrogenase/reductase by creating additional active pocket accommodating prochiral heterocyclic ketones

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Chem. Commun., 2023, Accepted Manuscript
DOI: 10.1039/D3CC04361D, Communication
Lei Qin, Xin Su, Jun Wang, Lunjie Wu, Man Zou, Jie Gu, Yan Xu, Yao Nie
Medium chain dehydrogenase/reductase (MDR) is a robust catalyst for the asymmetric synthesis of chiral heterocyclic alcohols, essential building blocks in pharmaceuticals. However, the regulatory mechanism of stereoselective complementary reduction of...
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