Facile and stereospecific synthesis of diverse β-N-glycosyl sulfonamide scaffolds via palladium catalysis

Chem. Commun., 2023, Advance Article
DOI: 10.1039/D3CC04063A, Communication
Lei Zhong, Qunliang Wang, Yujuan Wang, Yiyang Cheng, Yimeng Xiong, Haibo Peng, Zhen Zhou, Yun He, Yuanwei Dai
Diverse β-N-glycosulfonamido scaffolds were prepared by a palladium-catalysed stereospecific N-glycosylation. This tactic provides excellent opportunities for rapid construction of glycosyl sulfonamide libraries to stimulate glycodrug discovery.
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