A cellular platform for production of C4 monomers

Chem. Sci., 2023, Advance Article
DOI: 10.1039/D3SC02773B, Edge Article
Open Access Open Access
Matthew A. Davis, Vivian Yaci Yu, Beverly Fu, Miao Wen, Edward J. Koleski, Joshua Silverman, Charles A. Berdan, Daniel K. Nomura, Michelle C. Y. Chang
In this work, we describe the engineering of a microbial platform to produce six different C4 chemicals at near quantitative yields using a combination of metabolic engineering and directed evolution.
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