High and fast: NMR protein–proton side-chain assignments at 160 kHz and 1.2 GHz

Chem. Sci., 2023, 14,10824-10834
DOI: 10.1039/D3SC03539E, Edge Article
Open Access Open Access
Creative Commons Licence  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Morgane Callon, Dominique Luder, Alexander A. Malär, Thomas Wiegand, Václav Římal, Lauriane Lecoq, Anja Böckmann, Ago Samoson, Beat H. Meier
The combination of the fastest MAS and highest magnetic field allows to spectrally resolve the side-chain protons of proteins. It makes 1H-detected MAS NMR a key player in the study of protein interactions with other macromolecules or nucleic acids.
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