Chemodivergence in Pd-catalyzed desymmetrization of allenes: enantioselective [4+3] cycloaddition, desymmetric allenylic substitution and enynylation

Chem. Sci., 2023, 14,10812-10823
DOI: 10.1039/D3SC04581A, Edge Article
Open Access Open Access
Creative Commons Licence  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Pengfei Luo, Long Li, Xinfang Mao, Zheng Sun, Yingcheng Wang, Fangzhi Peng, Zhihui Shao
Pd-catalyzed enantioselective allenylic [4+3] cycloaddition, desymmetric allenylic substitution or tandem desymmetric allenylic substitution/β-vinylic hydrogen elimination (formal enynylation) can be realized chemodivergently by ligand control.
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