PET image-guided kidney injury theranostics enabled by a bipyramidal DNA framework

Biomater. Sci., 2024, 12,2086-2095
DOI: 10.1039/D3BM01575K, Paper
Open Access Open Access
Pinghui Li, Zhidie Huang, Xiaoyan Duan, Tao Wang, Shaowen Yang, Dawei Jiang, Jianbo Li
We constructed 68Ga-BDF and employed PET imaging to establish its pharmacokinetic model. BDF was eliminated from the body via the urinary system. We observed distinct imaging indicators in UUO and AKI mouse models. Furthermore, we observed the therapeutic effect of BDF on AKI.
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