Combining biomimetic collagen/hyaluronan hydrogels with discogenic growth factors promotes mesenchymal stroma cell differentiation into Nucleus Pulposus like cells

Biomater. Sci., 2023, Accepted Manuscript
DOI: 10.1039/D3BM01025B, Paper
Prince David Okoro, Antoine Frayssinet, Stephanie De Oliveira, Lea Rouquier, Gregor Miklosic, Matteo D'Este, Esther Potier, Christophe Helary
Based on stem cell injection into degenerated Nucleus Pulposus (NP), novel treatments for intervertebral disc (IVD) regeneration were disappointing because of cell leakage or inappropriate cell differentiation. In this study,...
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