Targeted microRNA delivery by lipid nanoparticles and gas vesicle-assisted ultrasound cavitation to treat heart transplant rejection

Biomater. Sci., 2023, 11,6492-6503
DOI: 10.1039/D2BM02103J, Paper
Rui Wang, Luyang Yi, Wuqi Zhou, Wenyuan Wang, Lufang Wang, Lingling Xu, Cheng Deng, Mengrong He, Yuji Xie, Jia Xu, Yihan Chen, Tang Gao, Qiaofeng Jin, Li Zhang, Mingxing Xie
Despite exquisite immune response modulation, the extensive application of microRNA therapy in treating heart transplant rejection is still impeded by poor stability and low target efficiency.
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