Enantioselective synthesis of tricyclic oxoquinolines via NHC-catalyzed Michael-aldol-lactamization-dehydration cascade

Chem. Commun., 2024, Advance Article
DOI: 10.1039/D4CC00502C, Communication
Shilpa Barik, Ganga Sankar, Akkattu T. Biju
NHC-catalyzed cascade reaction of enals with malonates bearing a 2-aminophenyl group leading to the enantioselective synthesis of tricyclic oxoquinolines via the chiral α,β-unsaturated acylazoliums is presented.
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