This review describes the behaviour of vinyl radicals produced through photoredox catalysis and how different reactivity patterns have been achieved by manipulating its chemistry. The focus has been on constructing various valuable scaffolds through 1,1-difunctionalization, 1,2-difunctionalization, and cyclization reactions.

Abstract

Organic chemistry has seen a surge in visible-light-driven transformations, which offer unique reaction pathways and access to new synthetic possibilities. We aim to provide a comprehensive understanding of state-of-the-art photo-mediated alkyne functionalization, with a focus on the reactive behavior of vinyl radicals. This review outlines our contributions to the field, including developing new methods for forming carbon-carbon and carbon-heteroatom bonds.