A convenient approach for the construction of 2-aminobenzothiazoles via I2-catalyzed tandem cyclization reaction of amines and carbon disulfide has been developed.
Comprehensive Summary
A convenient approach for the construction of 2-aminobenzothiazoles via I2-catalyzed tandem cyclization reaction of amines and carbon disulfide has been developed. The present approach starts from simple and readily available starting materials, affording a series of 2-aminobenzothiazoles in up to 89% yields under metal-free conditions. In this work, C—H/N—H functionalization was achieved and multiple C-hetero bonds were successfully constructed in one pot.