Synergistically remodulating H+/Ca2+ gradients to induce mitochondrial depolarization for enhanced synergistic cancer therapy

Chem. Sci., 2023, Advance Article
DOI: 10.1039/D3SC03493C, Edge Article
Open Access Open Access
Xiaoni Wang, Xiyang Ge, Xiaowen Guan, Jin Ouyang, Na Na
A DNA nanocomplex of Ca@DNA–MF was successfully prepared for synergistic three-channel mitochondrial depolarization via synergistically remodulating H+/Ca2+ gradients, providing a synergistic strategy for enhanced cancer therapy with low toxicity.
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