Dual-responsive PEG–lipid polyester nanoparticles for siRNA and vaccine delivery elicit anti-cancer immune responses by modulating tumor microenvironment

Biomater. Sci., 2023, 11,6619-6634
DOI: 10.1039/D3BM01265D, Paper
Zixu Liu, Linxuan Zhao, Yupeng Feng, Qingqing Wang, Nan Dong, Yu Zhang, Tian Yin, Haibing He, Xing Tang, Jingxin Gou, Li Yang
Dual-responsive PEG-lipid polyester nanoparticles (PEG BR647-NPs) were employed as a vaccine and STAT3 siRNA carrier for tumor-targeted delivery to modulate the tumor microenvironment.
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