Publication date: 30 October 2023
Source: Bioorganic & Medicinal Chemistry, Volume 94
Author(s): Marina Marinović, Hrvoje Rimac, Lais Pessanha de Carvalho, C. Rôla, S. Santana, Kristina Pavić, Jana Held, Miguel Prudêncio, Zrinka Rajić
Category Archives: Bioorganic & Medicinal Chemistry
Truxillic acid monoamides as fatty acid binding protein 5 inhibitors
Publication date: 30 October 2023
Source: Bioorganic & Medicinal Chemistry, Volume 94
Author(s): Chuanzhou Zhu, Livia Schutz, Kalani Jayanetti, Kathryn Takemura, Faniya Doswell, Liqun Wang, Iwao Ojima, Martin Kaczocha
Unraveling the unexpected aggregation behavior of Pyrazole-Based compounds Targeting Mycobacterium tuberculosis UDP-Galactopyranose mutase
Publication date: 30 October 2023
Source: Bioorganic & Medicinal Chemistry, Volume 94
Author(s): Dalia M. Ahmed, David A.R. Sanders
Design and synthesis of sulfonamides incorporating a biotin moiety: Carbonic anhydrase inhibitory effects, antiproliferative activity and molecular modeling studies
Publication date: 30 October 2023
Source: Bioorganic & Medicinal Chemistry, Volume 94
Author(s): Paloma Begines, Alessandro Bonardi, Alessio Nocentini, Paola Gratteri, Simone Giovannuzzi, Roberto Ronca, Camilla Tavani, Maria Luisa Massardi, Óscar López, Claudiu T. Supuran
Discovery of potential novel TRPC5 inhibitors by virtual screening and bioassay
Publication date: 30 October 2023
Source: Bioorganic & Medicinal Chemistry, Volume 94
Author(s): Meiling Shen, Lingfeng Li, Yue Li, Xi Gu, Longhui Bai, Chengfeng Xia, Wenyong Xiong, Zhili Zuo
Pentacyclic triterpene-amino acid derivatives induced apoptosis and autophagy in tumor cells, affected the JNK and PI3K/AKT/mTOR pathway
Publication date: 30 October 2023
Source: Bioorganic & Medicinal Chemistry, Volume 94
Author(s): Li-qiong Zhang, Li Sun, Yu-qing Zhou, Jing-jing Liu, Quan-de Wang, Wei-bin Mo, Ke-guang Cheng
DNA major versus minor groove occupancy of monomeric and dimeric crystal violet derivatives. Toward structural correlations
Publication date: 30 October 2023
Source: Bioorganic & Medicinal Chemistry, Volume 94
Author(s): Aren Mirzakhanian, Michael Khoury, Donald E. Trujillo, Byoula Kim, Donnie Ca, Thomas Minehan
Selenoneine-inspired selenohydantoins with glutathione peroxidase-like activity
Publication date: 30 October 2023
Source: Bioorganic & Medicinal Chemistry, Volume 94
Author(s): Rama Alhasan, Guilherme M. Martins, Pedro P. de Castro, Rahman Shah Zaib Saleem, Ali Zaiter, Isabelle Fries-Raeth, Alexandra Kleinclauss, Caroline Perrin-Sarrado, Patrick Chaimbault, Eufrânio N. da Silva Júnior, Caroline Gaucher, Claus Jacob
Structure-activity relationship studies and biological properties evaluation of peptidic NRP-1 ligands: Investigation of N-terminal cysteine importance
Publication date: 30 October 2023
Source: Bioorganic & Medicinal Chemistry, Volume 94
Author(s): Anna K. Puszko, Piotr Sosnowski, Olivier Hermine, Gérard Hopfgartner, Yves Lepelletier, Aleksandra Misicka
Selective modifications of lactose and <em>N-</em>acetyllactosamine with sulfate and aromatic bulky groups unveil unique structural insights in galectin-1-ligand recognition
Publication date: 30 October 2023
Source: Bioorganic & Medicinal Chemistry, Volume 94
Author(s): Mora Massaro, Alejandro J. Cagnoni, Francisco J. Medrano, Juan M. Pérez-Sáez, Shuay Abdullayev, Karima Belkhadem, Karina V. Mariño, Antonio Romero, René Roy, Gabriel A. Rabinovich