Category Archives: European Journal of Medicinal Chemistry

Hydrophobicity modulation <em>via</em> the substituents at positions 2 and 4 of 1,3,5-triazine to enhance therapeutic ability against Alzheimer’s disease for potent serotonin 5-HT<sub>6</sub>R agents

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Publication date: 15 November 2023

Source: European Journal of Medicinal Chemistry, Volume 260

Author(s): Sylwia Sudoł-Tałaj, Katarzyna Kucwaj-Brysz, Sabina Podlewska, Rafał Kurczab, Grzegorz Satała, Barbara Mordyl, Monika Głuch-Lutwin, Natalia Wilczyńska-Zawal, Magdalena Jastrzębska-Więsek, Kinga Czarnota-Łydka, Kinga Kurowska, Monika Kubacka, Ewa Żesławska, Wojciech Nitek, Agnieszka Olejarz-Maciej, Agata Doroz-Płonka, Anna Partyka, Gniewomir Latacz, Anna Wesołowska, Jadwiga Handzlik

An efficient site-selective, dual bioconjugation approach exploiting N-terminal cysteines as minimalistic handles to engineer tailored anti-HER2 affibody conjugates

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Publication date: 15 November 2023

Source: European Journal of Medicinal Chemistry, Volume 260

Author(s): Ana Novak, Florian Kersaudy, Sylvie Berger, Séverine Morisset-Lopez, François Lefoulon, Carlo Pifferi, Vincent Aucagne

Computational methods to analyze and predict the binding mode of inhibitors targeting both human and mushroom tyrosinase

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Publication date: 15 November 2023

Source: European Journal of Medicinal Chemistry, Volume 260

Author(s): Federico Ricci, Kristina Schira, Lyna Khettabi, Lisa Lombardo, Salvatore Mirabile, Rosaria Gitto, Montserrat Soler-Lopez, Jörg Scheuermann, Gerhard Wolber, Laura De Luca