Category Archives: European Journal of Medicinal Chemistry

Synthesis and evaluation of aromatic BDSF bioisosteres on biofilm formation and colistin sensitivity in pathogenic bacteria

Posted on by

Publication date: 5 December 2023

Source: European Journal of Medicinal Chemistry, Volume 261

Author(s): Andromeda-Celeste Gómez, Conor Horgan, Daniel Yero, Marc Bravo, Xavier Daura, Michelle O'Driscoll, Isidre Gibert, Timothy P. O'Sullivan

Strategies for developing retinoic acid receptor alpha-selective antagonists as novel agents for male contraception

Posted on by

Publication date: 5 December 2023

Source: European Journal of Medicinal Chemistry, Volume 261

Author(s): Md Abdullah Al Noman, Rebecca A.D. Cuellar, Jillian L. Kyzer, Sanny S.W. Chung, Narsihmulu Cheryala, Trinh A.D. Holth, Soma Maitra, Tahmina Naqvi, Henry L. Wong, Ernst Schönbrunn, Jon E. Hawkinson, Debra J. Wolgemuth, Gunda I. Georg

Evaluation of novel pyrazol-4-yl pyridine derivatives possessing arylsulfonamide tethers as c-Jun <em>N</em>-terminal kinase (JNK) inhibitors in leukemia cells

Posted on by

Publication date: 5 December 2023

Source: European Journal of Medicinal Chemistry, Volume 261

Author(s): Karim I. Mersal, Mohammed S. Abdel-Maksoud, Eslam M.H. Ali, Usama M. Ammar, Seyed-Omar Zaraei, Md Mamunul Haque, Tanuza Das, Noha F. Hassan, Eunice EunKyeong Kim, Jun-Seok Lee, HaJeung Park, Kwan Hyi Lee, Mohammed I. El-Gamal, Hee-Kwon Kim, Tamer M. Ibrahim, Chang-Hyun Oh

Design, synthesis and biological evaluation of novel 2,4-thiazolidinedione derivatives able to target the human BAG3 protein

Posted on by

Publication date: 5 December 2023

Source: European Journal of Medicinal Chemistry, Volume 261

Author(s): Federica Budassi, Chiara Marchioro, Martina Canton, Annagiulia Favaro, Mattia Sturlese, Chiara Urbinati, Marco Rusnati, Romeo Romagnoli, Giampietro Viola, Elena Mariotto