Real-time monitoring and actuation of a hybrid siphon valve for hematocrit-independent plasma separation from whole blood

Analyst, 2023, Advance Article
DOI: 10.1039/D3AN00862B, Paper
Reza Khodadadi, Esmail Pishbin, Manouchehr Eghbal, Karen Abrinia
Glass Slides are used as a super hydrophilic surfaces for making the hybrid siphon valves. This mechanism has been used for high efficiency plasma separation based on whole blood with different hematocrit levels.
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Electrochemiluminescence resonance energy transfer immunoassay based on a porphyrin metal–organic framework and AuNPs/NSG for the sensitive detection of zearalenone

Analyst, 2023, Advance Article
DOI: 10.1039/D3AN01418E, Paper
Xiaolin Fan, Xun Yao, Mengqi Qiu, Kang Wu, Anping Deng, Jianguo Li
A novel electrochemiluminescence resonance energy transfer (ECL-RET) system using porphyrin metal-organic framework (PCN-222) as a novel donor and AuNPs/NSG nanocomposites as the acceptor has been designed as well as applied in an immunosensor for detecting zearalenone (ZEN) in grain.
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Near-Infrared Fluorescent Probe for Detecting Hydrogen Sulfide with High Selectivity in Cells and Ulcerative Colitis Mice

Analyst, 2023, Accepted Manuscript
DOI: 10.1039/D3AN01442H, Paper
Chong-Kang Qin, Ling Yan, Zhi-Qing Wang, Guo Yu, Guo-Jiang Mao, Fen Xu, Chun-Yan Li
Although hydrogen sulfide (H2S) is a well-known toxic gas, its vital role as a gas transmitter in various physiological and pathological processes of living systems cannot be ignored. The relevant...
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Size-Exclusion Chromatography-Based Extracellular Vesicles Size Subtyping and Multiplex Membrane Protein Profiling for Differentiating Gastrointestinal Cancer Prognosis

Analyst, 2023, Accepted Manuscript
DOI: 10.1039/D3AN01027A, Paper
Ti Qin, Pinhao Li, Jun Li, Qianqian Guo, Ying Chen, Yu-E Wang, Ling Tao, Jian Huang, Xiangchun Shen, Xingjie Wu
Extracellular vesicles (EVs), as a type of subcellular structure, have been extensively researched for their potential in developing advanced diagnostic technologies for various diseases. However, the biomolecular and biophysical heterogeneity...
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Green Synthesis of N,S-Doped Carbon Dots for Tartrazine Detection and Antibacterial Activity

Analyst, 2023, Accepted Manuscript
DOI: 10.1039/D3AN01609A, Paper
Tanmayee Mohanta, Himadri Gourav Behuria, Santosh Kumar Sahu, Ashis K Jena, Swagatika Sahu
A simple, green and low cost method was developed for the synthesis of highly fluorescent N,S-doped carbon dots (N,S-CDs) via hydrothermal treatment of Gandha Prasarini leaves as a natural source...
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Breast tumor-on-chip: from tumor microenvironment to medical application

Analyst, 2023, Accepted Manuscript
DOI: 10.1039/D3AN01295F, Critical Review
Yiying Liu, Ruonan Liu, He Liu, Tong Lyu, Kun Chen, kaiming jin, Ye Tian
With the development of microfluidic technology, tumor-on-chip models gradually become a new tool for the study of breast cancer because they can simulate more key factors of tumor microenvironment compared...
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New synthetic red- and orange-emitting luciferases to upgrade in vitro and 3D cell biosensing

Analyst, 2023, Advance Article
DOI: 10.1039/D3AN01251D, Paper
Open Access Open Access
Maria Maddalena Calabretta, Denise Gregucci, Elisa Michelini
Two new luciferases, BoLuc and BrLuc, were obtained and characterized in terms of thermal and pH stability and emission properties, and in 3D mammalian cell bioassay for inflammation.
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Sensitively detecting endogenous homocysteine in human serum and cardiomyocytes with a specific fluorescent probe

Analyst, 2023, Accepted Manuscript
DOI: 10.1039/D3AN01430D, Paper
Huan Li, Qi wei Wang, Lili Shi, Tao Li
The elevated level of homocysteine (Hcy) in circulating blood is generally regarded as a risk factor for a variety of diseases including acute myocardial infarction (AMI), but there is no...
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Parahydrogen hyperpolarized NMR detection of underivatized short oligopeptides

Analyst, 2023, Advance Article
DOI: 10.1039/D3AN01345F, Paper
Nele Reimets, Kerti Ausmees, Sirje Vija, Aleksander Trummal, Merle Uudsemaa, Indrek Reile
Underivatized oligopeptides can be detected by parahydrogen hyperpolarized NMR in a biofluid sample. The method is supported by an experimental and DFT study of the underlying oligopeptide complexes with the iridium-based hyperpolarization catalyst.
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Influence of bovine and human serum albumin on the binding kinetics of biomolecular interactions

Analyst, 2023, Advance Article
DOI: 10.1039/D3AN01117H, Paper
Benjamin Charron, Alexandre Delorme, Caroline Dubois, Maryam Hojjat Jodaylami, Jean-Francois Masson
Bovine serum albumin (BSA) containing buffers are the standard blocking buffer in biosensing, yet different binding kinetics are observed with buffers containing human serum albumin (HSA) or human serum.
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