Multi-arm ε-polylysines exhibit broad-spectrum antifungal activities against Candida species

Biomater. Sci., 2023, Advance Article
DOI: 10.1039/D3BM01233F, Paper
Yuanqiao Cao, Ming Liu, Miaomiao Han, Shengxiang Ji
Multi-arm ε-polylysines (ε-mPLs, nR-Km) exhibit broad-spectrum antifungal activities and excellent biocompatibility. Mechanistic studies suggest that 3R-K7 kills fungi through entering the cells to generate ROS and induce cell apoptosis.
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Nanocarriers for Gene Delivery to the Cardiovascular System

Biomater. Sci., 2023, Accepted Manuscript
DOI: 10.1039/D3BM01275A, Review Article
Ling-Xin Shi, Xiu-Ran Liu, Ling-Yue Zhou, Zi-Qi Zhu, Qiong Yuan, Tao Zou
Cardiovascular diseases have posed a great threat to human health. Fortunately, gene therapy holds great promise in the fight against cardiovascular disease (CVD). In gene therapy, it is necessary to...
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Carbon network-hosted porphyrin as a highly biocompatible nanophotosensitizer for enhanced photodynamic therapy

Biomater. Sci., 2023, Advance Article
DOI: 10.1039/D3BM00992K, Paper
Min Wang, Yanlin Zheng, Huaming He, Tong Lv, Xin Xu, Xiao Fang, Chunhua Lu, Huanghao Yang
The carbon network-hosted porphyrins modifying the nucleus-targeting peptide (T-CPs) as highly biocompatible nanophotosensitizers avoided the aggregation-induced inactivation and in situ generated 1O2 in the nucleus for enhanced photodynamic therapy.
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X-ray Radio-Enhancement by Ti3C2Tx MXenes in Soft Tissue Sarcoma

Biomater. Sci., 2023, Accepted Manuscript
DOI: 10.1039/D3BM00607G, Paper
Open Access Open Access
Monika Zimmermann, Lukas Gerken, Shianlin Wee, Vera M. Kissling, Anna Lena Neuer, Elena Tsolaki, Alexander Gogos, Maria R. Lukatskaya, Inge Katrin Herrmann
Radiotherapy is an integral part of cancer therapy. Due to the low tissue specificity of radiation, damage to tumor-surrounding healthy tissue remains a major concern. Radio-enhancers based on inorganic nanomaterials...
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Near Infrared Light Activatable Niosomes Loaded with Indocyanine Green and Plasmonic Gold Nanorods for Theranostic Applications

Biomater. Sci., 2023, Accepted Manuscript
DOI: 10.1039/D3BM01187A, Paper
Prince Yumnam, Netra Hiremath, Raviraj Vankayala
Light mediated theranostic platforms involves the use of agents (small molecules/nanomaterials) which can absorb light to produce either heat or reactive chemical species (RCS) as well as emit fluorescence. Such...
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Combining biomimetic collagen/hyaluronan hydrogels with discogenic growth factors promotes mesenchymal stroma cell differentiation into Nucleus Pulposus like cells

Biomater. Sci., 2023, Accepted Manuscript
DOI: 10.1039/D3BM01025B, Paper
Prince David Okoro, Antoine Frayssinet, Stephanie De Oliveira, Lea Rouquier, Gregor Miklosic, Matteo D'Este, Esther Potier, Christophe Helary
Based on stem cell injection into degenerated Nucleus Pulposus (NP), novel treatments for intervertebral disc (IVD) regeneration were disappointing because of cell leakage or inappropriate cell differentiation. In this study,...
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A Polymer Network Architecture Provides Superior Cushioning and Lubrication of Soft Tissue Compared to a Linear Architecture

Biomater. Sci., 2023, Accepted Manuscript
DOI: 10.1039/D3BM00753G, Communication
Benjamin G Cooper, Christian D. DeMoya, Katie J. Sikes, David D. Frisbie, Nikki Phillips, Brad B. Nelson, C. Wayne McIlwraith, Chris E. Kawcak, Laurie R. Goodrich, Brian D. Snyder, Mark W. Grinstaff
We report the relationships between linear vs network polymer architecture and biomechanical outcomes including lubrication and cushioning when the polymers are applied to the surface of articulating knee cartilage. Aqueous...
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Engineered baicalein-decorated zinc phosphates for synergistic alleviation of inflammatory bowel disease by repairing mucosal barrier and relieving oxidative stress

Biomater. Sci., 2023, Accepted Manuscript
DOI: 10.1039/D3BM01284K, Paper
Limei Liu, Weisong Wu, Siqi Li, Li Ma, Yunting Liu, Xiaoli Wang, Yanjun Jiang
Orally administrating baicalein-decorated zinc phosphates (ZnBM) were engineered for mucosal barrier improvement and intestinal inflammation relief. ZnBM with a size of 1.78 µm comprised 5.58 wt% of baicalein and 13.17...
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Fluid flow-induced modulation of viability and osteodifferentiation of periodontal ligament stem cell spheroids-on-chip

Biomater. Sci., 2023, Advance Article
DOI: 10.1039/D3BM01011B, Paper
Open Access Open Access
Apurva Mishra, Ren Kai, Srividya Atkuru, Yichen Dai, Filippo Piccinini, Philip M. Preshaw, Gopu Sriram
Microfluidic spheroid-on-chip emulates physiologically relevant low fluid shear stress, resulting in improved PDLSC viability, enhanced osteodifferentiation, and uniform calcium deposition, offering new possibilities for periodontal research.
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Improve the effectiveness of Sonodynamic therapy: by optimizing components and combination with other treatments.

Biomater. Sci., 2023, Accepted Manuscript
DOI: 10.1039/D3BM00738C, Review Article
Xiangting Wang, Xiaohong Xu, Zhe Yang, Xuanshou Xu, Shisong Han, Heng Zhang
Sonodynamic therapy (SDT) is an emerging treatment method. In comparison to photodynamic therapy(PDT), SDT exhibits deep penetration, high cell membrane permeability, and free-expose to light capacity. Unfortunately, owing to inappropriate...
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