ABCD of IA: A multi-scale agent-based model of T cell activation in inflammatory arthritis

Biomater. Sci., 2024, 12,2041-2056
DOI: 10.1039/D3BM01674A, Paper
David A. McBride, James S. Wang, Wade T. Johnson, Nunzio Bottini, Nisarg J. Shah
The study develops a computational framework to model factors that lead to the evolution of autoreactive T cells in inflammatory arthritis. The results provide a tool for planning immunomodulatory strategies focused on new disease-modifying agents.
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Comparative analysis of supercritical fluid-based and chemical-based decellularization techniques for nerve tissue regeneration

Biomater. Sci., 2024, 12,1847-1863
DOI: 10.1039/D3BM02072J, Paper
Open Access Open Access
Beom-Seok Kim, Jeong-Uk Kim, Jae Woo Lee, Kyung Min Ryu, Rachel H. Koh, Kyoung-Ha So, Nathaniel S. Hwang
The supercritical (SC) fluid-based method were utilized for nerve tissue decellualrization. In vitrovivo assessments underscore its potential for advanced tissue engineering and regenerative applications.
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Self-assembled nanodrug delivery systems for anti-cancer drugs from traditional Chinese medicine

Biomater. Sci., 2024, 12,1662-1692
DOI: 10.1039/D3BM01451G, Review Article
Qiao Li, Yuan Lianghao, Gao Shijie, Wang Zhiyi, Tang Yuanting, Chen Cong, Zhao Chun-Qin, Fu Xianjun
In this review, we have summarized the common self-assembled mechanism of NSMs-based SANDDSs. Meanwhile, the potential applications for cancer treatment and future development prospects are also prospected.
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Gelatine–collagen photo-crosslinkable 3D matrixes for skin regeneration

Biomater. Sci., 2024, 12,1738-1749
DOI: 10.1039/D3BM01849K, Paper
Open Access Open Access
Gauthier Menassol, Boudewijn van der Sanden, Laetitia Gredy, Capucine Arnol, Thibaut Divoux, Donald K. Martin, Olivier Stephan
Immediate care of skin wounds and burns is essential to repair this mechanical and chemical barrier to infections.
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One-pot reaction for the preparation of diatom hemostatic particles with effective hemostasis and economic benefits

Biomater. Sci., 2024, 12,1883-1897
DOI: 10.1039/D3BM01793A, Paper
Yunji Sun, Chang Su, Jinfeng Liu, Zheng He, Shengting Che, Qinglan Wan, Jingyu Cai, Hao Zhan, Chao Feng, Xiaojie Cheng, Feng Lin, Junqiang Wei, Xiguang Chen
Diatom hemostatic particles prepared by one-pot reaction have streamlined process and mass production potential, can significantly stop bleeding and reduce accidental deaths.
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Self-adjuvanted L-arginine-modified dextran-based nanogels for sustained local antigenic protein delivery to antigen-presenting cells and enhanced cellular and humoral immune responses

Biomater. Sci., 2024, 12,1771-1787
DOI: 10.1039/D3BM01150J, Paper
Jin Teng Chung, Mehrnoosh Rafiei, Ying Chau
Antigens are delivered in self-adjuvanted arginine-modified dextran-based nanogels to the dendritic cells in promoting antigen specific cellular immunity.
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PET image-guided kidney injury theranostics enabled by a bipyramidal DNA framework

Biomater. Sci., 2024, 12,2086-2095
DOI: 10.1039/D3BM01575K, Paper
Open Access Open Access
Pinghui Li, Zhidie Huang, Xiaoyan Duan, Tao Wang, Shaowen Yang, Dawei Jiang, Jianbo Li
We constructed 68Ga-BDF and employed PET imaging to establish its pharmacokinetic model. BDF was eliminated from the body via the urinary system. We observed distinct imaging indicators in UUO and AKI mouse models. Furthermore, we observed the therapeutic effect of BDF on AKI.
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Extracellular vesicles produced by 3D cultured MSCs promote wound healing by regulating macrophage activation through ANXA1

Biomater. Sci., 2024, 12,1761-1770
DOI: 10.1039/D3BM02035E, Paper
Hao Deng, Yuheng Jiang, Junhao Deng, Feifan Chang, Junyu Chen, Xinyu Sun, Dongliang Cheng, Zhongqi Wang, Ran Li, Jiang Liu, Yi Li, Licheng Zhang, Pengbin Yin
Extracellular vesicles (EVs) produced by 3D-cultured MSCs can modulate macrophage activation through ANXA1, thereby promoting wound healing.
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Advanced postoperative tissue antiadhesive membranes enabled with electrospun nanofibers

Biomater. Sci., 2024, 12,1643-1661
DOI: 10.1039/D3BM02038J, Review Article
Yanting Zhu, Chenwei Zhang, Ying Liang, Jianyuan Shi, Qiuhao Yu, Shen Liu, Dengguang Yu, Hui Liu
Electrospun nanofibers with fascinating properties provide a versatile platform for postoperative tissue anti-adhesion.
The content of this RSS Feed (c) The Royal Society of Chemistry