Sorafenib and tetrakis (4-carboxyphenyl) porphyrin assembled nanoparticles for synergistic targeted chemotherapy and sonodynamic therapy of hepatocellular carcinoma

Biomater. Sci., 2024, 12,1864-1870
DOI: 10.1039/D3BM01994B, Paper
Yongzhi Chen, Qiuxia Tan, Yuanyu Tang, E. Pang, Rui Peng, Minhuan Lan, Dousheng Bai
Hepatocellular carcinoma (HCC) is characterized by a high degree of malignancy and mortality.
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Copper(II)-based metal–organic framework delivery of calcium ascorbate for enhanced chemodynamic therapy via H2O2 self-supply and glutathione depletion

Biomater. Sci., 2024, 12,1871-1882
DOI: 10.1039/D3BM01922E, Paper
Meng Zhang, Hongjin Xue, Jiaxin Yang, Xin Zhao, Mei Xue, Wei Sun, Jianfeng Qiu, Zhihong Zhu
A Cu/ZIF-8/Vc-Ca/HA nanosystem synchronously releases Fenton catalytic Cu2+ and Vc-Ca to achieve improved chemodynamic therapy via H2O2 self-supply and GSH depletion.
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Futuristic Alzheimer’s therapy: acoustic-stimulated piezoelectric nanospheres for amyloid reduction

Biomater. Sci., 2024, 12,1801-1821
DOI: 10.1039/D3BM01688A, Paper
Manju Sharma, Samraggi Choudhury, Anand Babu, Varun Gupta, Dipanjan Sengupta, Syed Afroz Ali, Mrunali D. Dhokne, Ashok Kumar Datusalia, Dipankar Mandal, Jiban Jyoti Panda
The graphical abstract portraying the utility of peizoactive polydopamine-coated PVDF nanospheres as potential therapeutic modalities for Alzheimer's disease. The nanospheres induced fibril disaggregation and neuroprotection upon acoustic activation in neural cells and animal model.
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Highly-ordered assembled organic fluorescent materials for high-resolution bio-sensing: a review

Biomater. Sci., 2024, 12,2019-2032
DOI: 10.1039/D3BM02070C, Review Article
Zheng Wang, Zilong Chen, Zhenhao Zhang, Hongzhen Wang, Haichang Zhang
Organic fluorescent materials (OFMs) play a crucial role in the development of biosensors, enabling the extraction of biochemical information within cells and organisms, extending to the human body.
The content of this RSS Feed (c) The Royal Society of Chemistry

Recent progress in nanomaterials for bacteria-related tumor therapy

Biomater. Sci., 2024, 12,1965-1980
DOI: 10.1039/D3BM01952G, Review Article
Fuping Zhang, Shuyu Wang, Shuo Yang, Feihe Ma, Hui Gao
Recent progress in nanomaterials for bacteria-related tumor therapy in terms of chemotherapy, immunotherapy and synergistic therapy is summarized in this review in order to provide some insights into this emerging and rapidly growing research area.
The content of this RSS Feed (c) The Royal Society of Chemistry

Biomaterial engineering strategies for B cell immunity modulations

Biomater. Sci., 2024, 12,1981-2006
DOI: 10.1039/D3BM01841E, Review Article
Open Access Open Access
Ali Zareein, Mina Mahmoudi, Shruti Sunil Jadhav, Joel Wilmore, Yaoying Wu
Biomaterials enhance B cell immunity by modulating the delivery approach, crosslinking B cell receptors, and promoting T cell help, while inhibitory co-receptor engagement via biomaterial design suppresses B cell function.
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A nanoparticle reinforced microporous methacrylated silk fibroin hydrogel to promote bone regeneration

Biomater. Sci., 2024, 12,2121-2135
DOI: 10.1039/D3BM01901B, Paper
Ruideng Wang, Xi He, Zhengyang Chen, Shilong Su, Jinwu Bai, Haifeng Liu, Fang Zhou
A photo-crosslinked nanocomposite hydrogel was prepared by incorporating an osteo-inductive inorganic nanoparticle for endogenous bone regeneration.
The content of this RSS Feed (c) The Royal Society of Chemistry

Dynamic monitoring of the fibrosis disease by a collagen targeting near infrared probe

Biomater. Sci., 2024, 12,1924-1931
DOI: 10.1039/D3BM01926H, Paper
Xiaoke Zhang, Qianwen Yang, Sensen Zhou, Cheng Li, Xiqun Jiang
A H2O2-sensitive macromolecular optical probe which can effectively bind to collagen was developed for real time noninvasive visualization of fibrotic tissues.
The content of this RSS Feed (c) The Royal Society of Chemistry