Prevention of esophageal stenosis via in situ cross-linkable alginate/gelatin powder in a new submucosal exfoliation model in rats

Biomater. Sci., 2023, 11,6781-6789
DOI: 10.1039/D3BM00887H, Paper
Qi Pan, Yosuke Tsuji, Athira Sreedevi Madhavikutty, Seiichi Ohta, Ayano Fujisawa, Natsuko F. Inagaki, Mitsuhiro Fujishiro, Taichi Ito
An in situ cross-linkable powder composed of alginate, gelatin, transglutaminase (TG), and calcium chloride ions (Ca2+) could prevent esophageal stenosis after endoscopic submucosal dissection (ESD) using novel rat ESD model.
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Graphene- and MXene-based materials for neuroscience: diagnostic and therapeutic applications

Biomater. Sci., 2023, 11,6687-6710
DOI: 10.1039/D3BM01114C, Review Article
Atefeh Zarepour, Çimen Karasu, Yousof Mir, Mohammad Hadi Nematollahi, Siavash Iravani, Ali Zarrabi
Therapeutic and diagnostic applications of graphene- and MXene-based materials in neuroscience are deliberated, focusing on important challenges and future prospects.
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Dendritic systems for bacterial outer membrane disruption as a method of overcoming bacterial multidrug resistance

Biomater. Sci., 2023, 11,6421-6435
DOI: 10.1039/D3BM01255G, Review Article
Kinga Skrzyniarz, Dorota Kuc-Ciepluch, Magdalena Lasak, Michał Arabski, Javier Sanchez-Nieves, Karol Ciepluch
Outer bacterial membrane disruption by dendritic systems as a way to overcome drug resistance.
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Prodrug-loaded semiconducting polymer hydrogels for deep-tissue sono-immunotherapy of orthotopic glioblastoma

Biomater. Sci., 2023, 11,6823-6833
DOI: 10.1039/D3BM00585B, Paper
Liyun Zhu, Xing Wang, Mengbin Ding, Ningyue Yu, Yijing Zhang, Hongwei Wu, Qin Zhang, Jiansheng Liu, Jingchao Li
A novel sono-activatable prodrug hydrogel was developed to achieve deep-tissue sono-immunotherapy of orthotopic glioblastoma.
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Acid-sensitive stable polymeric micelle-based oxidative stress nanoamplifier as immunostimulating anticancer nanomedicine

Biomater. Sci., 2023, 11,6600-6610
DOI: 10.1039/D3BM00770G, Paper
Gayoung Kwon, Jinsu Baek, Nuri Kim, Soonyoung Kwon, Nanhee Song, Seong-Cheol Park, Byeong-Su Kim, Dongwon Lee
Oxidative stress amplifying compounds that not only generate reactive oxygen species (ROS) but also deplete antioxidants could elicit selective killing of cancer cells with minimal toxicity to normal cells and also induce immunogenic cell death (ICD).
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Development of digital light processing-based multi-material bioprinting for fabrication of heterogeneous tissue constructs

Biomater. Sci., 2023, 11,6663-6673
DOI: 10.1039/D3BM01054F, Paper
Hao Su, Bingxian Lu, Ming Li, Xue Yang, Minghao Qin, Yang Wu
A DLP-based multi-material bioprinting process was developed which mitigated bioink cross-contamination, damage to printed features, and waste of bioink. Constructs with multiple materials and complex structures could be readily obtained.
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Synthesis, characterization, and biological verification of asialoglycoprotein receptor-targeted lipopolysaccharide-encapsulated PLGA nanoparticles for the establishment of a liver fibrosis animal model

Biomater. Sci., 2023, 11,6650-6662
DOI: 10.1039/D3BM01058A, Paper
Ching-Ju Huang, Shao-Jung Hsu, Yi-Chiung Hsu, Liang-Kun Chen, Chuan Li, Hui-Chun Huang, Yu-Hsiang Lee
ALPNPs with hepatocytic targetability can specifically induce hepatic fibrosis and exhibit significantly less toxicity in organs other than the liver in comparison to free LPS after 14-day treatment.
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Efficient fabrication of thermo-stable dissolving microneedle arrays for intradermal delivery of influenza whole inactivated virus vaccine

Biomater. Sci., 2023, 11,6790-6800
DOI: 10.1039/D3BM00377A, Paper
Jihui Lee, Martin Beukema, Oliwia A. Zaplatynska, Conor O'Mahony, Wouter L. J. Hinrichs, Anke L. W. Huckriede, Joke A. Bouwstra, Koen van der Maaden
WIV incorporated dMNAs produced by the dispensing method reduced antigen waste by 95% compared to the centrifugation method. They also maintained the stability of WIV and elicited similar immune responses to intramuscularly (I.M.) delivered WIV.
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Fabrication and in vitro investigation of hyperbranched poly-lysine-grafted warp knitted polypropylene sling for potential treatment of stress urinary incontinence

Biomater. Sci., 2023, 11,6504-6523
DOI: 10.1039/D3BM00943B, Paper
Shuying Zhao, Meiqi Fang, Yan Li, Fujun Wang, Hao Li, Lu Wang
Hyperbranched polylysine grafted polypropylene warp-knitted sling with mechanical compliance to prevent postoperative erosion.
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