Association between low-sodium salt intervention and long-term blood pressure changes is modified by ENaC genetic variation: A gene-diet interaction analysis in a randomized controlled trial

Food Funct., 2023, Accepted Manuscript
DOI: 10.1039/D3FO02393A, Paper
Hao Sun, Ying Zhou, Shuyi Jiang, Dan Zhao, Huamin Li, Yue Lu, Bing Ma, Bo Zhou
Background: Hypertension is closely associated with excessive sodium intake, and low-sodium salt has been shown to lower blood pressure. However, whether low-sodium salt interacts with genetic variation related to salt...
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Comparison of taste mechanism of umami and bitter peptide from fermented mandarin fish (Chouguiyu) based on molecular docking and electronic tongue technology

Food Funct., 2023, Accepted Manuscript
DOI: 10.1039/D3FO02697C, Paper
Chungsheng Li, Daqiao Yang, L. Li, Yueqi Wang, Shengjun Chen, Yongqiang Zhao, Wanling Lin
Unclear taste mechanisms of peptides limit rapid screening of taste peptides with high intensity. In this study, the taste mechanisms of umami and bitter peptides from Chouguiyu was compared. After...
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Structural Properties of Kudzu Protein Enzymatic Hydrolysate and Their Repair Effect on HepG2 Cells Damaged by H2O2 Oxidation

Food Funct., 2023, Accepted Manuscript
DOI: 10.1039/D3FO02988C, Paper
Hui-na Pang, Yihan YUE, Hongying DONG, Ting JIANG, Hongyin Zhang, Zhao Yu, Tiequan CAI, Mingming Yan, Shuai Shao
We investigated the structural properties, foaming capacity and foaming stability, antioxidant activity, and amino acid composition of Kudzu protein (KP) and Kudzu protein hydrolysate (KPH). The peptide sequence of KPH...
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Association between the composite dietary antioxidant index and chronic kidney disease: evidence from NHANES 2011–2018

Food Funct., 2023, Advance Article
DOI: 10.1039/D3FO01157G, Paper
Open Access Open Access
Min Wang, Zhao-hui Huang, Yong-hong Zhu, Ping He, Qiu-Ling Fan
There is growing evidence that antioxidant-rich diets protect against chronic kidney disease (CKD).
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Critical review on phytochemical profiles and health-promoting effects of mushroom Armillaria mellea

Food Funct., 2023, Accepted Manuscript
DOI: 10.1039/D3FO02334F, Review Article
Kaiyuan Huang, Baojun Xu
Research on the nutritional and medicinal properties of wild edible mushrooms has witnessed a significant surge in recent years. Among these mushrooms, Armillaria mellea (AM) stands out due to its...
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Unleashing lactoferrin’s antidepressant potential through the PI3K/Akt/mTOR pathway in chronic restraint stress rats

Food Funct., 2023, Advance Article
DOI: 10.1039/D3FO02222F, Paper
Hanan H. Ahmed, Reham M. Essam, Muhammed F. El-Yamany, Kawkab A. Ahmed, Ayman E. El-Sahar
The effects of CRS on inducing depression and the beneficial effect of LF in halting depression through mitigating ROS and pro-inflammatory cytokines, restoring corticosterone, 5-HT and BDNF levels, and modulating the hippocampal PI3K/Akt/mTOR/GSK-3β pathway were studied.
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Maize near-isogenic lines with enhanced flavonoids alleviated dextran sodium sulfate-induced murine colitis via modulation of the gut microbiota

Food Funct., 2023, Advance Article
DOI: 10.1039/D3FO02953K, Paper
Binning Wu, Abigail D. Cox, Haotian Chang, Mary Kennett, Cristina Rosa, Surinder Chopra, Shiyu Li, Lavanya Reddivari
Anthocyanins and phlobaphenes enriched maize lines restored intestinal barrier function, mucosal integrity and modulated gut microbiota to display a protective effect against DSS-induced colitis.
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The effect of n-3 polyunsaturated fatty acid supplementation on cognitive function outcomes in the elderly depends on the baseline omega-3 index

Food Funct., 2023, Accepted Manuscript
DOI: 10.1039/D3FO02959J, Review Article
Xin He, Hongzhuan Yu, Jiacheng Fang, Zhongshi Qi, Shengjie Pei, Bei Yan, Run Liu, Qiuzhen Wang, Ignatius Man-Yau Szeto, Biao Liu, Lei Chen, Duo Li
Both epidemiological and preclinical studies showed the benefits of n-3 polyunsaturated fatty acid (n-3 PUFA) on dementia and cognitive impairment. While the results of clinical randomized controlled trials (RCTs) were...
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Pectic oligosaccharides ameliorates high-fat diet-induced obesity and hepatic steatosis in association with modulating gut microbiota in mice

Food Funct., 2023, Accepted Manuscript
DOI: 10.1039/D3FO02168H, Paper
Shengnan Yu, Haoyu Wang, Luwen Cui, Jingyi Wang, Zixuan Zhang, Zhinan Wu, Xiaoqian Lin, Ningning He, Yuanqiang Zou, Shangyong Li
Accumulating evidences show that gut microbiota and its metabolites have important significance in the etiology of obesity and related disorders. Prebiotics enable prevent and alleviate obesity through modulation of the...
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Astaxanthin nanoparticles ameliorate dextran sulfate sodium-induced colitis by alleviating oxidative stress, regulating intestinal flora, and protecting the intestinal barrier

Food Funct., 2023, Advance Article
DOI: 10.1039/D3FO03331G, Paper
Mengfan Luo, Qiaoyue Yuan, Mingzhen Liu, Xingye Song, Yingjie Xu, Tao Zhang, Xiaoqun Zeng, Zhen Wu, Daodong Pan, Yuxing Guo
This study aimed to develop a novel astaxanthin nanoparticle using gum arabic (GA) and whey protein powder enriched with milk fat globule membranes (MFGM-WPI) as carriers and to investigate its effect and alleviation mechanism on colitis in mice.
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