Publication date: 5 December 2023
Source: European Journal of Medicinal Chemistry, Volume 261
Author(s): Lu Mao, Song Wang, Ying Qu, Haixia Wang, Yifan Zhao, Chuantao Zhu, Zhongmou Zhang, Chengyun Jin, Piet Herdewijn, Feng-Wu Liu, Zhenya Wang
Synthesis, cytotoxic activity evaluation and mechanistic investigation of novel 3,7-diarylsubstituted 6-azaindoles
Publication date: 5 December 2023
Source: European Journal of Medicinal Chemistry, Volume 261
Author(s): Nikolaos Lougiakis, Nikolaos Sakalis, Maria Georgiou, Panagiotis Marakos, Nicole Pouli, Alexios-Leandros Skaltsounis, Eleni Mavrogonatou, Harris Pratsinis, Dimitris Kletsas
Synthesis and biological evaluation of fluoroquinolones containing a pyridoxine derivatives moiety
Publication date: 5 December 2023
Source: European Journal of Medicinal Chemistry, Volume 261
Author(s): Nikita V. Shtyrlin, Airat R. Kayumov, Maria N. Agafonova, Marsel R. Garipov, Alina E. Gatina, Mikhail V. Pugachev, Elena S. Bulatova, Denis Y. Grishaev, Alfiya G. Iksanova, Rail M. Khaziev, Ilnur M. Ganiev, Aleksandr M. Aimaletdinov, Oleg I. Gnezdilov, Yurii G. Shtyrlin
Galantamine-memantine hybrids for Alzheimer’s disease: The influence of linker rigidity in biological activity and pharmacokinetic properties
Publication date: 5 December 2023
Source: European Journal of Medicinal Chemistry, Volume 261
Author(s): Filippo Basagni, Jose A. Ortega, Sine M. Bertozzi, Andrea Armirotti, Maria Summa, Rosalia Bertorelli, Manuela Bartolini, Ian R. Mellor, Martina Bedeschi, Giovanni Bottegoni, Vittorio Lembo, Anna Minarini, Andrea Cavalli, Michela Rosini
Development of a NIR fluorescent probe for fluorescence-assisted EGFR-TKI applicable patients screening and drug resistance monitoring
Publication date: 5 December 2023
Source: European Journal of Medicinal Chemistry, Volume 261
Author(s): Xinmiao Lu, Muyu Wu, Quanyong Luo
Exploring novel anticancer pyrazole benzenesulfonamides featuring tail approach strategy as carbonic anhydrase inhibitors
Publication date: 5 December 2023
Source: European Journal of Medicinal Chemistry, Volume 261
Author(s): Rehab F. Ahmed, Walaa R. Mahmoud, Nagwa M. Abdelgawad, Marwa A. Fouad, Mona F. Said
Synthesis and evaluation of aromatic BDSF bioisosteres on biofilm formation and colistin sensitivity in pathogenic bacteria
Publication date: 5 December 2023
Source: European Journal of Medicinal Chemistry, Volume 261
Author(s): Andromeda-Celeste Gómez, Conor Horgan, Daniel Yero, Marc Bravo, Xavier Daura, Michelle O'Driscoll, Isidre Gibert, Timothy P. O'Sullivan
Kinetic modelling of the P-glycoprotein mediated efflux with a large-scale matched molecular pair analysis
Publication date: 5 December 2023
Source: European Journal of Medicinal Chemistry, Volume 261
Author(s): Hongtao Zhao
Strategies for developing retinoic acid receptor alpha-selective antagonists as novel agents for male contraception
Publication date: 5 December 2023
Source: European Journal of Medicinal Chemistry, Volume 261
Author(s): Md Abdullah Al Noman, Rebecca A.D. Cuellar, Jillian L. Kyzer, Sanny S.W. Chung, Narsihmulu Cheryala, Trinh A.D. Holth, Soma Maitra, Tahmina Naqvi, Henry L. Wong, Ernst Schönbrunn, Jon E. Hawkinson, Debra J. Wolgemuth, Gunda I. Georg
Evaluation of novel pyrazol-4-yl pyridine derivatives possessing arylsulfonamide tethers as c-Jun <em>N</em>-terminal kinase (JNK) inhibitors in leukemia cells
Publication date: 5 December 2023
Source: European Journal of Medicinal Chemistry, Volume 261
Author(s): Karim I. Mersal, Mohammed S. Abdel-Maksoud, Eslam M.H. Ali, Usama M. Ammar, Seyed-Omar Zaraei, Md Mamunul Haque, Tanuza Das, Noha F. Hassan, Eunice EunKyeong Kim, Jun-Seok Lee, HaJeung Park, Kwan Hyi Lee, Mohammed I. El-Gamal, Hee-Kwon Kim, Tamer M. Ibrahim, Chang-Hyun Oh