Publication date: 5 December 2023
Source: European Journal of Medicinal Chemistry, Volume 261
Author(s): Jiyoung Jeon, Sun Young Jang, Eun Joo Kwak, Sun Hoe Lee, Joo-Yun Byun, Yu-Yon Kim, Young Gil Ahn, Pargat Singh, Kyeongwon Moon, In Su Kim
Design, synthesis and biological evaluation of novel 2,4-thiazolidinedione derivatives able to target the human BAG3 protein
Publication date: 5 December 2023
Source: European Journal of Medicinal Chemistry, Volume 261
Author(s): Federica Budassi, Chiara Marchioro, Martina Canton, Annagiulia Favaro, Mattia Sturlese, Chiara Urbinati, Marco Rusnati, Romeo Romagnoli, Giampietro Viola, Elena Mariotto
Discovery of novel G9a/GLP covalent inhibitors for the treatment of triple-negative breast cancer
Publication date: 5 December 2023
Source: European Journal of Medicinal Chemistry, Volume 261
Author(s): Qiangsheng Zhang, Bo Chang, Qiang Feng, Lu Li
Natural phytoalexins inspired the discovery of new biphenyls as potent antifungal agents for treatment of invasive fungal infections
Publication date: 5 December 2023
Source: European Journal of Medicinal Chemistry, Volume 261
Author(s): Jian-Chuan Liu, Jian Yang, Shu-Xin Lei, Ming-Fan Wang, Yan-Ni Ma, Rui Yang
Integrated fragment-based drug design and virtual screening techniques for exploring the antidiabetic potential of thiazolidine-2,4-diones: Design, synthesis and <em>in vivo</em> studies
Publication date: 5 December 2023
Source: European Journal of Medicinal Chemistry, Volume 261
Author(s): Shankar Gupta, Gurkaran Singh Baweja, Shamsher Singh, Mehdi Irani, Rajveer Singh, Vivek Asati
Synthesis of cell penetrating peptide sterol coupler and its liposome study on S-mRNA
Publication date: 5 December 2023
Source: European Journal of Medicinal Chemistry, Volume 261
Author(s): Yuan Li, Wenlin Ma, Wen Su, Zhihong Yan, Lin Jia, Jie Deng, Ali Zhu, Yanbo Xie, Xinyi Li, Wanhui Shao, Yuman Ma, Linze Che, Tao Zhu, Haomeng Wang, Mingyuan Li, Peng Yu
Design and synthesis of 1<em>H</em>-benzo[<em>d</em>]imidazole selective HDAC6 inhibitors with potential therapy for multiple myeloma
Publication date: 5 December 2023
Source: European Journal of Medicinal Chemistry, Volume 261
Author(s): Linfu Liu, Liyuan Zhang, Xuxi Chen, Kang Yang, Hao Cui, Rui Qian, Shanshan Zhao, Liqun Wang, Xiaolan Su, Manyu Zhao, Mengzhu Wang, Zan Hu, Tao Lu, Yong Zhu, Qing-Qing Zhou, Yuqin Yao
Investigation of novel 5ʹ-amino adenosine derivatives with potential anti-Zika virus activity
Publication date: 5 December 2023
Source: European Journal of Medicinal Chemistry, Volume 261
Author(s): Xingjuan Chen, Yunzheng Yan, Huijuan Song, Zhuang Wang, Apeng Wang, Jingjing Yang, Rui Zhou, Shijie Xu, Shaokang Yang, Wei Li, Xiaoyu Qin, Qingsong Dai, Mingliang Liu, Kai Lv, Ruiyuan Cao, Wu Zhong
Synthesis and application of small molecules approved for the treatment of lymphoma
Publication date: 5 December 2023
Source: European Journal of Medicinal Chemistry, Volume 261
Author(s): Yuan-Yuan Guo, Jing-Yi Zhang, Jin-Feng Sun, Peng Nie, Hua Gao
Discovery and optimization of indirubin derivatives as novel ferroptosis inducers for the treatment of colon cancer
Publication date: 5 December 2023
Source: European Journal of Medicinal Chemistry, Volume 261
Author(s): Jiang-Min Zhu, Chen Chen, Min Kong, Ling Zhu, Ya-Lin Li, Jian-Fei Zhang, Zhan-Peng Yu, Shi-Shu Xu, Ling-Yi Kong, Jian-Guang Luo