Publication date: 15 November 2023
Source: Bioorganic & Medicinal Chemistry Letters, Volume 96
Author(s): Jianjun Fang, Xuemei Dong, Lixin Sun, Jie Sun, Chengjun Dong, Rongchen Wang, Chunchang Zhao
Synthesis and preliminary biological evaluation of a novel <sup>99m</sup>Tc-labeled small molecule for PD-L1 imaging
Publication date: 15 November 2023
Source: Bioorganic & Medicinal Chemistry Letters, Volume 96
Author(s): Dandan Zhu, Xiang Xu, Pei Zou, Yaling Liu, Hongyong Wang, Guoqing Han, Chunxiong Lu, Minhao Xie
Synthesis and biological activity assay of novel camptothecin-peptidic conjugates based on PEPT1
Publication date: 15 November 2023
Source: Bioorganic & Medicinal Chemistry Letters, Volume 96
Author(s): Qiang Zhang, Ping Zou, Meixuan Zhu, Dan Sui, Shaoming Wang, Zhiwei Hu, Yang Wang, Lijia Jing, Jian Zheng
SARS-CoV-2 papain-like protease (PLpro) inhibitory and antiviral activity of small molecule derivatives for drug leads
Publication date: 15 November 2023
Source: Bioorganic & Medicinal Chemistry Letters, Volume 96
Author(s): Arun K. Ghosh, Dana Shahabi, Mackenzie E.C. Imhoff, Satish Kovela, Ashish Sharma, Shin-ichiro Hattori, Nobuyo Higashi-Kuwata, Hiroaki Mitsuya, Andrew D. Mesecar
Fluorinated aldosterone synthase (CYP11B2)-inhibitors for differential diagnosis between bilateral and unilateral conditions of primary aldosteronism
Publication date: 15 November 2023
Source: Bioorganic & Medicinal Chemistry Letters, Volume 96
Author(s): Philipp Maier, Britta Heinze, Sabine Gabor, Samario Reese, Stefanie Hahner, Andreas Schirbel
Inhibitory effect of γ-ray-modified hydroxymethylated baicalins on NO production
Publication date: 15 November 2023
Source: Bioorganic & Medicinal Chemistry Letters, Volume 96
Author(s): Gyeong Han Jeong, Hanui Lee, Hong-Ki Lee, Hyo Jin Choi, Byung Yeoup Chung, Hyoung-Woo Bai
Benzimidazole derivatives as tubulin polymerization inhibitors: Design, synthesis and <em>in vitro</em> cytotoxicity studies
Publication date: 15 November 2023
Source: Bioorganic & Medicinal Chemistry Letters, Volume 96
Author(s): Kritika Laxmikeshav, Ziaur Rahman, Ashutosh Mahale, Durgesh Gurukkala Valapil, Pravesh Sharma, Joel George, Regur Phanindranath, Manoj P. Dandekar, Onkar P. Kulkarni, Narayana Nagesh, Nagula Shankaraiah
Total and chemoenzymatic synthesis of the lipodepsipeptide rhizomide A
Publication date: 15 November 2023
Source: Bioorganic & Medicinal Chemistry Letters, Volume 96
Author(s): Corinne A. Lepetit, André R. Paquette, Jordan T. Brazeau-Henrie, Christopher N. Boddy
SAR study of niclosamide derivatives for neuroprotective function in SH-SY5Y neuroblastoma
Publication date: 15 November 2023
Source: Bioorganic & Medicinal Chemistry Letters, Volume 96
Author(s): Shizue Mito, Benxu Cheng, Benjamin A. Garcia, Xin Yee Ooi, Daniela Gonzalez, Tess C. Ruiz, Francisco X. Elisarraras, Andrew Tsin
Discovery of Novel Dual Bruton’s Tyrosine Kinase (BTK) and Janus Kinase 3 (JAK3) Inhibitors as A Promising Strategy for Rheumatoid Arthritis
Publication date: Available online 27 May 2023
Source: Bioorganic & Medicinal Chemistry
Author(s): Tingting Liang, Lifang Cen, Junjie Wang, Ming Cheng, Weibo Guo, Wenjie Wang, Chunqiu Yu, Haifeng Zhang, Yuan Wang, Zhongyan Hao, Jiaming Jin, Yaoyao Wu, Teng Jiang, Qihua Zhu, Yungen Xu