Publication date: Available online 9 August 2023
Source: Bioorganic & Medicinal Chemistry
Author(s): Wenqiang Zhang, Ruonan Ning, Ting Ran, Qi Peng, Yong Liu, Tao Lu, Yadong Chen, Min Jiang, Yu Jiao
<em>In situ</em> Click Chemistry-based Discovery of 1,2,3-triazole-derived Diarylpyrimidines as Novel HIV-1 NNRTIs by Exploiting the Tolerant Region I in Binding Pocket
Publication date: Available online 23 September 2023
Source: Bioorganic & Medicinal Chemistry
Author(s): Yanying Sun, Da Feng, Zhenzhen Zhou, Tao Zhang, Erik De Clercq, Christophe Pannecouque, Dongwei Kang, Peng Zhan, Xinyong Liu
Target discovery of bioactive natural products with Native-compound-Coupled CNBr-activated Sepharose 4B Beads (NCCB): applications, mechanisms and outlooks
Publication date: Available online 26 September 2023
Source: Bioorganic & Medicinal Chemistry
Author(s): Yueteng Zhang, Junjie Zhang, Menglong Li, Yan Qiao, Wei Wang, Lu Ma, Kangdong Liu
The mechanisms of multidrug resistance of breast cancer and research progress on related reversal agents
Publication date: Available online 30 September 2023
Source: Bioorganic & Medicinal Chemistry
Author(s): Shiwen Yu, Jinling Zheng, Yan Zhang, Dandan Meng, Yujue Wang, Xiaoyu Xu, Na Liang, Shayibai Shabiti, Xu Zhang, Zixi Wang, Zehua Yang, Pengbing Mi, Xing Zheng, Wenjun Li, Hongfei Chen
A novel genetically-encoded bicyclic peptide inhibitor of human urokinase-type plasminogen activator with better cross-reactivity toward the murine orthologue
Publication date: Available online 12 October 2023
Source: Bioorganic & Medicinal Chemistry
Author(s): Ylenia Mazzocato, Stefano Perin, Julia Morales-Sanfrutos, Zhanna Romanyuk, Stefano Pluda, Laura Acquasaliente, Giuseppe Borsato, Vincenzo De Filippis, Alessandro Scarso, Alessandro Angelini
Mass spectrometric assays monitoring the deubiquitinase activity of the SARS-CoV-2 papain-like protease inform on the basis of substrate selectivity and have utility for substrate identification
Publication date: Available online 12 October 2023
Source: Bioorganic & Medicinal Chemistry
Author(s): Lennart Brewitz, H.T. Henry Chan, Petra Lukacik, Claire Strain-Damerell, Martin A. Walsh, Fernanda Duarte, Christopher J. Schofield
Reading and erasing of histone crotonyllysine mimics by the AF9 YEATS domain and SIRT2 deacylase
Publication date: Available online 12 October 2023
Source: Bioorganic & Medicinal Chemistry
Author(s): Nurgül Bilgin, Vildan A. Türkmen, Nesrin Hammami, Nadja R. Christensen, Jordi C. J. Hintzen, Jasmin Mecinović
Editorial Board
Publication date: 30 October 2023
Source: Bioorganic & Medicinal Chemistry, Volume 94
Author(s):
Design, synthesis and antiplasmodial evaluation of new amide-, carbamate-, and ureido-type harmicines
Publication date: 30 October 2023
Source: Bioorganic & Medicinal Chemistry, Volume 94
Author(s): Marina Marinović, Hrvoje Rimac, Lais Pessanha de Carvalho, C. Rôla, S. Santana, Kristina Pavić, Jana Held, Miguel Prudêncio, Zrinka Rajić
Truxillic acid monoamides as fatty acid binding protein 5 inhibitors
Publication date: 30 October 2023
Source: Bioorganic & Medicinal Chemistry, Volume 94
Author(s): Chuanzhou Zhu, Livia Schutz, Kalani Jayanetti, Kathryn Takemura, Faniya Doswell, Liqun Wang, Iwao Ojima, Martin Kaczocha