Org. Biomol. Chem., 2023, 21,7717-7723
DOI: 10.1039/D3OB01137B, Paper

Open Access

  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Sarah J. Pike, Richard Telford, Louise Male
A versatile and short synthetic route to access a photo-responsive foldamer has been established. The robustness of the reversible conformational switching of the foldamer has been determined using UV/Vis, 1H NMR and circular dichroism spectroscopy.
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Org. Biomol. Chem., 2023, 21,7917-7923
DOI: 10.1039/D3OB01056B, Paper

Gaurang J. Bhatt, Pradeep T. Deota, Narayan N. Som, Darshil Shah
An aesthetically pleasing prototype decacyclic ring system resembling the shape of a butterfly has been synthesized in four simple steps. Diels–Alder reactions on a tetrasubstituted double bond give rise to the formation of its analogues.
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Org. Biomol. Chem., 2023, 21,7753-7757
DOI: 10.1039/D3OB01182H, Paper

Open Access

  This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Daniel Alonso-Carrillo, Israel Carreira-Barral, Marcin Mielczarek, Andrea Sancho-Medina, Enara Herran, Claudia Vairo, Angel Del Pozo, Iris Luzuriaga, Nerea Lazcanoiturburu, Oihane Ibarrola, Sara Ponce, María Villar-Vidal, María García-Valverde, Roberto Quesada
Nanostructured lipid carriers (NLCs) can be used to efficiently formulate highly lipophilic anionophores. These formulations are able to deliver these compounds to phospholipid membranes maintaining their anion transport activity.
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Org. Biomol. Chem., 2023, 21,7724-7729
DOI: 10.1039/D3OB01150J, Paper

Debabrata Das, Krishna Gopal Ghosh, Sumit Garai, Chandu Palasetty, Sureshkumar Devarajulu
A sustainable organo-photocatalyzed approach for carbothioaryl/alkylation of activated alkenes has been revealed via multi-component C(sp³)–H bond functionalization under a redox-neutral environment.
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Org. Biomol. Chem., 2023, 21,7702-7706
DOI: 10.1039/D3OB01247F, Communication

Open Access

  This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Alessio M. Caramiello, Maria Cristina Bellucci, Emerenziana Ottaviano, Silvia Ancona, Elisa Borghi, Alessandro Volonterio
Three model hydantoin-based universal peptidomimetics were designed, synthetized, and investigated as Gram positive and Gram negative antimicrobial agents.
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Org. Biomol. Chem., 2023, 21,7758-7766
DOI: 10.1039/D3OB00925D, Paper

Alexander S. Budnikov, Igor B. Krylov, Andrey V. Lastovko, Roman A. Dolotov, Mikhail I. Shevchenko, Alexander O. Terent'ev
The intermolecular oxime radical addition to CC bonds was discovered employing stable and reactive diacetyliminoxyl as a novel free-radical reagent.
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Org. Biomol. Chem., 2023, 21,7691-7695
DOI: 10.1039/D3OB01270K, Communication

Vishnu Mishra, Hosahalli S. Udaya, Venkataramanarao G. Anand
Maximum confusion in porphyrinoids can be achieved by inter-linking heterocycles only through 2,4-connectivity.
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Org. Biomol. Chem., 2023, 21,7730-7752
DOI: 10.1039/D3OB01169K, Paper

Tobias Winge, Dirk Schepmann, Judith Schmidt, Constantin Daniliuc, Ernst-Ulrich Würthwein, Bernhard Wünsch
According to DFT calculations, the synthesis of spirocyclic σ₁ ligands involves two aza-Michael additions or a [4 + 2] cycloaddition. Dispiro ligand with a high number of sp³ C-atoms shows promising σ₁ affinity, selectivity and physicochemical properties.
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Org. Biomol. Chem., 2023, 21,7707-7711
DOI: 10.1039/D3OB01031G, Communication

Nalladhambi Neerathilingam, Sakthivel Prabhu, Ramasamy Anandhan
A facile electrochemical synthesis of phthalimides from o-phthalaldehyde and amines was achieved via tandem cyclocondensation and α-C–H oxygenation under mild conditions.
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Org. Biomol. Chem., 2023, 21,7891-7894
DOI: 10.1039/D3OB01165H, Communication

Haruki Ohno, Ryosuke Takahashi, Takuya Suga, Takahiro Soeta, Yutaka Ukaji
Divergent transformation of C,N-cyclic-N′-acyl azomethine imines by ethyl diazoacetate and trimethylsilyldiazomethane was achieved to give α-diazoacetate moiety-introduced tetrahydroisoquinolines and 3-benzazepine derivatives respectively.
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