Tunable full-color emission of stilbazoles containing a 2-halo-3,4-dicyanopyridine acceptor

Org. Biomol. Chem., 2023, 21,7935-7943
DOI: 10.1039/D3OB01326J, Paper
Anastasia I. Ershova, Sergey V. Fedoseev, Sergey A. Blinov, Mikhail Yu. Ievlev, Konstantin V. Lipin, Oleg V. Ershov
Synthesis of a series of novel push–pull stilbazole-based chromophores with tunable multicolor emission ranging from 442 nm to 710 nm and covering the whole visible spectrum is reported.
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Cell internalization kinetics and surface charge accessibility of surface-modified PAMAM dendrimers

Org. Biomol. Chem., 2023, 21,7782-7790
DOI: 10.1039/D3OB01265D, Paper
Carola F. Díaz, Diego L. Cifuentes, Maximiliano Oyarzún, Verónica A. Jiménez, Leonardo Guzmán
The accessibility of surface cationic charges is a key determinant for the cell internalization capacity of surface-modified PAMAM dendrimers with acetyl, folate or poly(ethylene glycol) groups.
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A reaction-based scenario for fluorescence probing of Au(III) ions in human cells and plants

Org. Biomol. Chem., 2023, 21,7880-7885
DOI: 10.1039/D3OB01081C, Communication
Merve Çevik Eren, Ahmet Eren, Suay Dartar, Beraat Umur Kaya, Muhammed Üçüncü, Canan Varlikli, Hüseyin Çağlar Karakaya, Mustafa Emrullahoğlu
In the presence of gold ions, a BODIPY construct with an extended π-conjugation transforms into a new structure with a relatively short π-system, which can be monitored as distinct changes in the color of the emission in plants and human cells.
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The development of a broad-spectrum retaining β-exo-galactosidase activity-based probe

Org. Biomol. Chem., 2023, 21,7813-7820
DOI: 10.1039/D3OB01261A, Paper
Chi-Lin Kuo, Qin Su, Adrianus M. C. H. van den Nieuwendijk, Thomas J. M. Beenakker, Wendy A. Offen, Lianne I. Willems, Rolf. G. Boot, Alexi J. Sarris, André R. A. Marques, Jeroen D. C. Codée, Gijsbert A. van der Marel, Bogdan I. Florea, Gideon J. Davies, Herman S. Overkleeft, Johannes M. F. G. Aerts
Acid β-galactosidase (GLB1) and galactocerebrosidase (GALC) are retaining exo-β-galactosidases involved in lysosomal glycoconjugate metabolism.
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Dioxygen concentration-dependent selective hydroxysulfonylation of olefins by rose bengal-sensitized photocatalysis

Org. Biomol. Chem., 2023, 21,7994-8002
DOI: 10.1039/D3OB01162C, Paper
Navin Yadav, Soumen Payra, Parag Tamuly, Jarugu Narasimha Moorthy
A facile visible light-mediated synthesis of β-hydroxysulfones selectively from olefins and sulfonyl hydrazides/N-hydroxy sulfonamides in the presence of rose bengal as a photocatalyst and dioxygen as an oxidant is described.
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Recent progress in photoinduced direct desulfurization of thiols

Org. Biomol. Chem., 2023, 21,7873-7879
DOI: 10.1039/D3OB01274C, Review Article
Yuhong Ma, Jinfei Deng, Jianyu Gu, Dengbo Jiang, Kaizhuo Lv, Xiushen Ye, Qiuli Yao
Light-driven desulfurization and coupling reactions of mercaptans in the modification of glycosides, proteins, polymers, and deuterated compounds are reviewed.
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Lactam-fused tropolones: a new tunable, environmentally sensitive fluorophore class

Org. Biomol. Chem., 2023, 21,7900-7907
DOI: 10.1039/D3OB01263H, Communication
Daniel V. Schiavone, Joel Gallardo, Diana M. Kapkayeva, John-Charles Baucom, Ryan P. Murelli
Lactam-fused tropolones are easily accessible, environmentally-responsive fluorophores with broad emissions profiles.
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Sequential detection of inflammation-related hypochlorite ions and viscosity with a relay fluorescent probe

Org. Biomol. Chem., 2023, 21,7808-7812
DOI: 10.1039/D3OB00967J, Paper
Yu-Qing Zhang, Zhi-Nan Kang, Jing-Jie Ming, Sheng-Nan Suo, Jia-Ling Kang, Hai Xu, Ya-Wen Wang, Yu Peng
A new fluorescent probe has been developed for relay detection of hypochlorite ions and viscosity.
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Branched montbretin A mimics allow derivatisation and potent amylase inhibition

Org. Biomol. Chem., 2023, 21,7977-7983
DOI: 10.1039/D3OB01051A, Paper
Matthew Calvert, Ryan P. Sweeney, Hong-Ming Chen, Harbir Bajwa, Seyed A. Nasseri, Davood Habibi, Stephen G. Withers
Structure-based design of a branched version of a high affinity amylase inhibitor based on the natural product montbretin A allows derivatization and manipulation of physical properties while retaining potent (nM) inhibition.
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Electrochemical selenium-catalyzed para-amination of N-aryloxyamides: access to polysubstituted aminophenols

Org. Biomol. Chem., 2023, 21,7895-7899
DOI: 10.1039/D3OB01116J, Communication
Lei Gao, Zhi-Feng Wang, Lin-Wei Wang, Hai-Tao Tang, Zu-Yu Mo, Mu-Xue He
We have developed a mild method for selenium catalyzed intramolecular rearrangement of N-aryloxyamides to produce para amination products under electrochemical conditions. The method has the advantages of high efficiency, high atom utilization and environmental friendliness.
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