Studies on the [4 + 2] cycloaddition and allylic substitution of indole-fused zwitterionic π-allylpalladium

Org. Biomol. Chem., 2023, Advance Article
DOI: 10.1039/D3OB01451G, Paper
Zhengyu Han, Yu Xue, Xiang Li, Xinzhe Hu, Xiu-Qin Dong, Jianwei Sun, Hai Huang
A new kind of indole-fused zwitterionic π-allylpalladium precursor compound has been designed and synthesized.
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A turn-on fluorescent probe for selective detection of H2S in environmental samples and bio-imaging in human breast cancer cells

Org. Biomol. Chem., 2023, 21,8020-8030
DOI: 10.1039/D3OB01319G, Paper
Dipanjan Banik, Anirban Karak, Satyajit Halder, Shilpita Banerjee, Moumi Mandal, Anwesha Maiti, Kuladip Jana, Ajit Kumar Mahapatra
A turn-on fluorescent probe TPB-NO2 was synthesized for rapid detection of H2S in environmental and biological samples. A bright cyan colour was observed due to the PET mechanism.
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A kinetics study of copper-catalysed click reactions in ionic liquids

Org. Biomol. Chem., 2023, 21,7984-7993
DOI: 10.1039/D3OB00237C, Paper
Diana Sloboda, Cameron C. Weber, Eduards Bakis
In this study, we discovered that both the structure of the ionic liquid and the catalyst exert a significant influence on the copper(I)-catalyzed azide–alkyne cycloaddition reaction rate.
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Visible-light-promoted organic-dye-catalyzed sulfonylation/cyclization to access indolo[2,1-a]isoquinoline derivatives

Org. Biomol. Chem., 2023, Advance Article
DOI: 10.1039/D3OB01289A, Paper
Yucai Tang, Jinglin Duan, Biyu Yang, Yupeng He, Changyuan Du, Xiangyang Zhang
An efficient visible-light-promoted organic-dye-catalyzed radical cascade cyclization was developed for the rapid synthesis of sulfonyl-substituted indolo[2,1-a]isoquinolines and benzimidazo[2,1-a]isoquinolin-6(5H)-ones.
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InCl3-catalyzed intramolecular carbonyl–olefin metathesis

Org. Biomol. Chem., 2023, Advance Article
DOI: 10.1039/D3OB01170D, Paper
Marianela G. Pizzio, Zoe B. Cenizo, Luciana Méndez, Ariel M. Sarotti, Ernesto G. Mata
We describe a novel synthetic strategy for intramolecular carbonyl–olefin metathesis based on InCl3 catalysis and a sustainably attractive protocol.
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A safety-catch protecting group strategy compatible with Boc-chemistry for the synthesis of peptide nucleic acids (PNAs)

Org. Biomol. Chem., 2023, Advance Article
DOI: 10.1039/D3OB01348K, Paper
Open Access Open Access
K. P. Nandhini, Sikabwe Noki, Edikarlos Brasil, Fernando Albericio, Beatriz G. de la Torre
The use of a safety-catch protecting scheme allows the synthesis of PNAs using the Boc as temporal protecting group.
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Phosphite–imidazole catalyzed N-formylation and N-acylation of amines

Org. Biomol. Chem., 2023, Advance Article
DOI: 10.1039/D3OB01306E, Paper
Babak Kaboudin, Hesam Esfandiari, Meysam Kakavand, Masoumeh Sohrabi, Elahe Yousefian Amirkhiz, Abdollah Neshat, Teru Kawazoe, Haruhiko Fukaya, Hikaru Yanai
The N-formylation reaction of amines with DMF as a formylating agent was developed. N-Sulfonyl amidines were also obtained in good to excellent yields by the reaction of sulfonamides with DMF under similar conditions.
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A facile approach to phenothiazinones via catalytic aerobic oxidation: discovery of an antiproliferative agent

Org. Biomol. Chem., 2023, Advance Article
DOI: 10.1039/D3OB01111A, Paper
Su-Hui Ji, Qian Wang, Yun-Rui Cai
A facile and robust synthesis of phenothiazinones with TEMPO-based catalytic system under an ambient atmosphere is presented.
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