Matrix stiffness triggers chemoresistance through elevated autophagy in pancreatic ductal adenocarcinoma

Biomater. Sci., 2023, Advance Article
DOI: 10.1039/D3BM00598D, Paper
Haopeng Pan, Shajun Zhu, Tiancheng Gong, Di Wu, Yahong Zhao, Jiashuai Yan, Chaolun Dai, Yan Huang, Yumin Yang, Yibing Guo
Matrix stiffness based on GelMA hydrogel triggers chemoresistance to gemcitabine through autophagy in pancreatic ductal adenocarcinoma.
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3D printing microporous scaffolds from modular bioinks containing sacrificial, cell-encapsulating microgels

Biomater. Sci., 2023, Advance Article
DOI: 10.1039/D3BM00721A, Paper
Alexis J. Seymour, David Kilian, Renato S. Navarro, Sarah M. Hull, Sarah C. Heilshorn
Blending sacrificial, cell-laden microgels with structural, UV-crosslinkable microgels produces a family of modular bioinks with tunable void fractions that influence cellular morphology while maintaining a depth-independent cell distribution.
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Zwitterionic silver nanoparticle based antibacterial eye drops for efficient therapy of bacterial keratitis

Biomater. Sci., 2023, Advance Article
DOI: 10.1039/D3BM01346D, Paper
Yangjing Bai, Li Ma, Yingchun Huang, Shiying Lang, Wenjie Fan, Gongyan Liu
Inefficient biofilm clearance and the risk of drug resistance pose significant challenges for antibiotic eye drops in the treatment of bacterial keratitis (BK).
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A covalent organic framework-derived M1 macrophage mimic nanozyme for precise tumor-targeted imaging and NIR-II photothermal catalytic chemotherapy

Biomater. Sci., 2023, Advance Article
DOI: 10.1039/D3BM01206A, Paper
Peng Gao, Kaixian Wang, Ruyue Wei, Xiaoying Shen, Wei Pan, Na Li, Bo Tang
A M1 macrophage membrane-cloaked biomimetic nanosystem was fabricated for tumor-targeted imaging, drug delivery and NIR-II photothermal-catalysis-enhanced chemotherapy of breast cancer.
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Chlorogenic Acid Releasing Microspheres Enhanced Electrospun Conduit to Promote Peripheral Nerve Regeneration

Biomater. Sci., 2023, Accepted Manuscript
DOI: 10.1039/D3BM00920C, Paper
Jia-Qi Fang, Xue-Han Jin, Bo Xu, Liping Nan, Shuhao Liu, Jian-Guang Wang, Na Niu, Zhong Wu, Feng Chen, Jun-Jian Liu
Chlorogenic acid (CGA) has been confirmed as a polyphenol, and existing research has suggested the high bioactivity of CGA for therapeutic effects on a wide variety of diseases. Despite the...
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Bioinspired immuno-radio-enhancers toward synergistic nanomedicine through radiation-induced abscopal effects and immunocheckpoint blockade therapies

Biomater. Sci., 2023, Accepted Manuscript
DOI: 10.1039/D3BM01144E, Communication
Pengfei Zhang, Hu Chen, Chuan Chen, Xuan Liu, Hongwei Cheng, Yaming Wu, Xiaoyong Wang, Gang Liu, Yun Zeng
The use of local radiotherapy in combination with immunotherapy has attracted great interest to obtain local cancer control. A versatile drug delivery platform for an MRI-guided immuno/radio-therapy (RT) strategy, which...
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From rosin to novel bio-based silicone rubber :A review

Biomater. Sci., 2023, Accepted Manuscript
DOI: 10.1039/D3BM01308A, Review Article
Qiaoguang Li, Yuxin He, Jie Yan, Yongquan Li, Junfeng Feng, Zhihong Wang
Rosin is the characteristic natural renewable resources and one of the important chemical raw materials in China. In view of the unique hydrogenated phenanthrene ring skeleton structure of rosin, the...
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Lipid-assisted PEG-b-PLA nanoparticles with ultrahigh SN38 loading capability for efficient cancer therapy

Biomater. Sci., 2023, Advance Article
DOI: 10.1039/D3BM01469J, Paper
Xiaoyi Huang, Jieyi Li, Yanfang Yang, Zi-Lu Wang, Xian-Zhu Yang, Zi-Dong Lu, Cong-Fei Xu
Lipid-assisted PEG-b-PLA nanoparticles achieve stable and ultrahigh SN38 entrapment through attenuating intermolecular π–π stacking of SN38 for efficient cancer therapy.
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ECM proteins and cationic polymers coating promote dedifferentiation of patient-derived mature adipocytes to stem cells

Biomater. Sci., 2023, Advance Article
DOI: 10.1039/D3BM00934C, Paper
Aslı Sena Karanfil, Fiona Louis, Yoshihiro Sowa, Michiya Matsusaki
Reprogramming of mature adipocytes is an attractive research area due to the plasticity of these cells.
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Progress and future prospects of hemostatic materials based on nanostructured clay minerals

Biomater. Sci., 2023, Accepted Manuscript
DOI: 10.1039/D3BM01326J, Review Article
Yinfeng Yang, Xiaomei Wang, Fangfang Yang, Bin Mu, Aiqin Wang
The occurrence of uncontrolled hemorrhage is a significant threat to human life and health, and despite remarkable advances in biomaterials in the past decade, it remains a challenge to develop...
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