Effect of pre-analytical variables on Raman and FTIR spectral content of lymphocytes

Analyst, 2023, Advance Article
DOI: 10.1039/D3AN00686G, Paper
Open Access Open Access
Jade F. Monaghan, Daniel Cullen, Claire Wynne, Fiona M. Lyng, Aidan D. Meade
This work describes how pre-analytical variables such as sample handling, storage and processing can influence the biochemical signature of lymphocytes.
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Ultrasensitive detection of thiram based on surface-enhanced Raman scattering via Au@Ag@Ag core/shell/shell bimetallic nanorods

Analyst, 2023, Advance Article
DOI: 10.1039/D3AN00821E, Paper
Yuqiu Wang, Shuchang Liu, Yongjun Hu, Cuicui Fu, Weiqiang Chen
We developed a sensitive and stable SERS-active substrate of Au@Ag@Ag core/shell/shell nanorods, formed by encapsulating Au nanorods into a bilayer silver shell with Raman reporter molecules (4-mercaptobenzoic acid and thiram) in shell–shell gap.
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Rapid fabrication of hydrophobic/hydrophilic patterns on paper substrates for paper spray mass spectrometry

Analyst, 2023, Advance Article
DOI: 10.1039/D3AN01071F, Paper
Austin Arias, Peyton E. Windham, Natalie A. Cheyne, William M. Gilliland
Substrates for paper spray mass spectrometry can be rapidly coated and patterned using silanes followed by oxygen/plasma treatment. Creating channels in the paper improves detection of antiretrovirals in a neat matrix and in urine.
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Electrochemiluminescence resonance energy transfer immunoassay based on a porphyrin metal–organic framework and AuNPs/NSG for the sensitive detection of zearalenone

Analyst, 2023, Advance Article
DOI: 10.1039/D3AN01418E, Paper
Xiaolin Fan, Xun Yao, Mengqi Qiu, Kang Wu, Anping Deng, Jianguo Li
A novel electrochemiluminescence resonance energy transfer (ECL-RET) system using porphyrin metal-organic framework (PCN-222) as a novel donor and AuNPs/NSG nanocomposites as the acceptor has been designed as well as applied in an immunosensor for detecting zearalenone (ZEN) in grain.
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Influence of bovine and human serum albumin on the binding kinetics of biomolecular interactions

Analyst, 2023, Advance Article
DOI: 10.1039/D3AN01117H, Paper
Benjamin Charron, Alexandre Delorme, Caroline Dubois, Maryam Hojjat Jodaylami, Jean-Francois Masson
Bovine serum albumin (BSA) containing buffers are the standard blocking buffer in biosensing, yet different binding kinetics are observed with buffers containing human serum albumin (HSA) or human serum.
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Parahydrogen hyperpolarized NMR detection of underivatized short oligopeptides

Analyst, 2023, Advance Article
DOI: 10.1039/D3AN01345F, Paper
Nele Reimets, Kerti Ausmees, Sirje Vija, Aleksander Trummal, Merle Uudsemaa, Indrek Reile
Underivatized oligopeptides can be detected by parahydrogen hyperpolarized NMR in a biofluid sample. The method is supported by an experimental and DFT study of the underlying oligopeptide complexes with the iridium-based hyperpolarization catalyst.
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Sensitively detecting endogenous homocysteine in human serum and cardiomyocytes with a specific fluorescent probe

Analyst, 2023, Accepted Manuscript
DOI: 10.1039/D3AN01430D, Paper
Huan Li, Qi wei Wang, Lili Shi, Tao Li
The elevated level of homocysteine (Hcy) in circulating blood is generally regarded as a risk factor for a variety of diseases including acute myocardial infarction (AMI), but there is no...
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New synthetic red- and orange-emitting luciferases to upgrade in vitro and 3D cell biosensing

Analyst, 2023, Advance Article
DOI: 10.1039/D3AN01251D, Paper
Open Access Open Access
Maria Maddalena Calabretta, Denise Gregucci, Elisa Michelini
Two new luciferases, BoLuc and BrLuc, were obtained and characterized in terms of thermal and pH stability and emission properties, and in 3D mammalian cell bioassay for inflammation.
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Breast tumor-on-chip: from tumor microenvironment to medical application

Analyst, 2023, Accepted Manuscript
DOI: 10.1039/D3AN01295F, Critical Review
Yiying Liu, Ruonan Liu, He Liu, Tong Lyu, Kun Chen, kaiming jin, Ye Tian
With the development of microfluidic technology, tumor-on-chip models gradually become a new tool for the study of breast cancer because they can simulate more key factors of tumor microenvironment compared...
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Green Synthesis of N,S-Doped Carbon Dots for Tartrazine Detection and Antibacterial Activity

Analyst, 2023, Accepted Manuscript
DOI: 10.1039/D3AN01609A, Paper
Tanmayee Mohanta, Himadri Gourav Behuria, Santosh Kumar Sahu, Ashis K Jena, Swagatika Sahu
A simple, green and low cost method was developed for the synthesis of highly fluorescent N,S-doped carbon dots (N,S-CDs) via hydrothermal treatment of Gandha Prasarini leaves as a natural source...
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