Volume 41, Issue 3-4, July-December 2022, Page 205-232
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Mobilization and scavenging of Ni + 2 and Cd + 2 from binary metal ions mixture to study the influence of co-cation on biosorption
Residue monitoring and dietary risk assessment of chlorantraniliprole and tolfenpyrad in Chinese kale under open‑field conditions
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DNA‐Encoded Libraries and Their Application to RNA
Abstract
The functional roles of structured RNAs in the regulation of biological processes, and hence RNA's potential as an effective therapeutic target, have only recently been appreciated. Robust and high-throughput methods that identify potent RNA ligands are critical to the development of chemical probes and therapeutics. DNA-encoded libraries (DEL) technology has emerged as a powerful tool for protein ligand discovery, and its ability to generate large, custom-tailored, and novel chemical space offers unprecedented opportunities to discover the rules of RNA ligand design. In this review, we discuss the basic principles of DEL selection, current progress on the application of DEL to RNA targets, and the outlook of targeting RNA by DEL.
Synthesis, crystal structure, spectroscopic, and Hirshfeld surface study of a new functionalized α-hydroxyphosphonate complex of tin(IV) chloride
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A review on advancement of biosensors for the detection of amphetamine drug
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Statement of Retraction: A Zn(II)-based coordination polymer: reduced the nicotinic acetylcholine receptors levels and exerted analgesic activity after total knee arthroplasty
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Statement of Retraction: Structural characterization and anti-liver cancer activity of a Cu(II)-based coordination polymer
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Statement of Retraction: A new mixed-ligand Co(II)-phosphonate framework: inhibited the wnt signaling pathway and exerted promotion activity on fracture rehabilitation
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Statement of Retraction: A new Cu(II)-based coordination polymer: structural determination and anti-rectal cancer activity
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