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Author Archives: Joey H. Li

MEF2C regulates NK cell effector functions through control of lipid metabolism

Posted on 8 April 2024 by Joey H. Li

Nature Immunology, Published online: 08 April 2024; doi:10.1038/s41590-024-01811-2

Here the authors identify the transcription factor MEF2C as essential for human NK cell function and viral immunity in mice and humans. This control is exerted via regulation of lipid metabolism, and deficiency in MEF2C can be overcome by oleic acid supplementation.
Posted in Nature Immunology
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