Autoreactive B cells against malondialdehyde-induced protein cross-links are present in the joint, lung, and bone marrow of rheumatoid arthritis patients

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Publication date: Available online 4 October 2023

Source: Journal of Biological Chemistry

Author(s): Peter Sahlström, Vijay Joshua, Viktoriia Valkovskaia, Charlotte Biese, Ragnhild Stålesen, Lena Israelsson, Ákos Végvári, Dagmar Scheel-Toellner, Lars Klareskog, Monika Hansson, Aase Hensvold, Vivianne Malmström, Caroline Grönwall

The C-terminal domain of the anti-amyloid chaperone DNAJB6 binds to Amyloid-β peptide fibrils and inhibits secondary nucleation

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Publication date: Available online 4 October 2023

Source: Journal of Biological Chemistry

Author(s): Nicklas Österlund, Rebecca Frankel, Andreas Carlsson, Dev Thacker, Maja Karlsson, Vanessa Matus, Astrid Gräslund, Cecilia Emanuelsson, Sara Linse

Mycobacterial RNase E cleaves with a distinct sequence preference and controls the degradation rates of most <em>Mycolicibacterium smegmatis</em> mRNAs

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Publication date: Available online 5 October 2023

Source: Journal of Biological Chemistry

Author(s): Ying Zhou, Huaming Sun, Abigail R. Rapiejko, Diego A. Vargas-Blanco, Maria Carla Martini, Michael R. Chase, Samantha R. Joubran, Alexa B. Davis, Joseph P. Dainis, Jessica M. Kelly, Thomas R. Ioerger, Louis A. Roberts, Sarah M. Fortune, Scarlet S. Shell

‘Affimer’ synthetic protein scaffolds block oxidized LDL binding to the LOX-1 scavenger receptor and inhibit ERK1/2 activation

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Publication date: Available online 5 October 2023

Source: Journal of Biological Chemistry

Author(s): Barnaby W.R. Roper, Christian Tiede, Izma Abdul-Zani, Gary A. Cuthbert, Dhananjay Jade, Ahmed Al-Aufi, William R. Critchley, Queen Saikia, Shervanthi Homer-Vanniasinkam, Tatsuya Sawamura, Michael J. McPherson, Michael A. Harrison, Darren C. Tomlinson, Sreenivasan Ponnambalam