Publication date: October 2023
Source: Biochemical Pharmacology, Volume 216
Author(s): Eveliina Korhonen, Niina Piippo, Maria Hytti, Kai Kaarniranta, Anu Kauppinen
Upregulation of IL-37 in epithelial cells: A potential new mechanism of T cell inhibition induced by tacrolimus
Publication date: October 2023
Source: Biochemical Pharmacology, Volume 216
Author(s): Zhangci Su, Jingyi Lu, Zihang Ling, Wei Li, Xi Yang, Bin Cheng, Xiaoan Tao
Triazolothiadiazine derivative positively modulates CXCR4 signaling and improves diabetic wound healing
Publication date: October 2023
Source: Biochemical Pharmacology, Volume 216
Author(s): Satyamaheshwar Peddibhotla, Karly Caples, Alka Mehta, Qi-Yin Chen, Junyi Hu, Shaquia Idlett-Ali, Liping Zhang, Carlos Zgheib, Junwang Xu, Kenneth W. Liechty, Siobhan Malany
Eicosapentaenoic acid metabolites promotes the trans-differentiation of pancreatic α cells to β cells
Publication date: October 2023
Source: Biochemical Pharmacology, Volume 216
Author(s): Chaofeng Xing, Minyi Tang, Jianqin Yang, Shuai Wang, Qihua Xu, Wenbin Feng, Yunping Mu, Fanghong Li, Allan Zijian Zhao
An <em>in vitro</em> assay to investigate venom neurotoxin activity on muscle-type nicotinic acetylcholine receptor activation and for the discovery of toxin-inhibitory molecules
Publication date: October 2023
Source: Biochemical Pharmacology, Volume 216
Author(s): Rohit N. Patel, Rachel H. Clare, Line Ledsgaard, Mieke Nys, Jeroen Kool, Andreas H. Laustsen, Chris Ulens, Nicholas R. Casewell
Tazemetostat synergistically combats multidrug resistance by the unique triple inhibition of ABCB1, ABCC1, and ABCG2 efflux transporters <em>in vitro</em> and <em>ex vivo</em>
Publication date: October 2023
Source: Biochemical Pharmacology, Volume 216
Author(s): Youssif Budagaga, Ziba Sabet, Yu Zhang, Eva Novotná, Ivo Hanke, Tomáš Rozkoš, Jakub Hofman
Nicotinic acid attenuates experimental non-alcoholic steatohepatitis by inhibiting the NLRP3 inflammasome/pyroptosis pathway
Publication date: October 2023
Source: Biochemical Pharmacology, Volume 216
Author(s): Irina Cardoso-Lezama, Miguel Á. Fuentes-Figueroa, Erika Ramos-Tovar, Linda V. Márquez-Quiroga, Arturo Ortiz-Fernández, Eduardo E. Vargas-Pozada, Jaime Arellanes-Robledo, Víctor Tsutsumi, Pablo Muriel
Febuxostat alleviates Arsenic Trioxide-Induced renal injury in Rats: Insights on the crosstalk between NLRP3/TLR4, Sirt-1/NF-κB/TGF-β signaling Pathways, and miR-23b-3p, miR-181a-5b expression
Publication date: October 2023
Source: Biochemical Pharmacology, Volume 216
Author(s): Basel A. Abdel-Wahab, Ehab A.M. El-Shoura, Mohammed Shafiuddin Habeeb, Dalia Zafaar
Sesamin ameliorates lipotoxicity and lipid accumulation through the activation of the estrogen receptor alpha signaling pathway
Publication date: October 2023
Source: Biochemical Pharmacology, Volume 216
Author(s): Thi Hoa Pham, Gi Ho Lee, Sun Woo Jin, Seung Yeon Lee, Eun Hee Han, Nam Doo Kim, Chul Yung Choi, Gil-Saeng Jeong, Sang Ki Lee, Hyung Sik Kim, Hye Gwang Jeong
Targeting the RET tyrosine kinase in neuroblastoma: A review and application of a novel selective drug design strategy
Publication date: October 2023
Source: Biochemical Pharmacology, Volume 216
Author(s): Erica A. Steen, Mariam Basilaia, William Kim, Taelor Getz, Jeffrey L. Gustafson, Peter E. Zage